Department of Hematology, Versilia's Hospital, Viale Aurelia, 335, 55049 Camaiore, Italy.
Hematology Unit, Bnai Zion Medical Center, Haifa 3339419, Israel.
Nutrients. 2024 Jan 11;16(2):237. doi: 10.3390/nu16020237.
Multiple Myeloma (MM) is the second most prevalent hematologic malignancy, and its incidence has been increasing enormously in recent years. The prognosis of MM has changed radically with the introduction of new drugs that have improved life expectancy; recurrences are a common occurrence during the course of the disease and are characterized by an increase in refractory to treatment. Moreover, MM patients are challenged by quality of life-related concerns while limited conventional therapy may be offered. This includes bone pain and dialysis due to the complications of acute renal failure. We, therefore, believe that it is very important to add new treatment modalities, including supplements, nutritional modifications, acupuncture, and mind-body therapies, with the goal of improving treatment tolerance, effectiveness, and patients' quality of life. Moreover, many patients use some of these supplements on their own, in the hope of reducing the side effects, so it is even more important to know their action and potential. The purpose of this review is to illustrate all these strategies potentially available to enrich our approach to this, to date, incurable disease.
多发性骨髓瘤（MM）是第二大常见的血液系统恶性肿瘤，近年来其发病率呈显著上升趋势。随着新药物的引入，MM 的预后已经发生了根本性变化，这些药物延长了患者的预期寿命；然而，疾病过程中经常会出现复发，并且这些复发具有难治性的特点。此外，MM 患者还面临与生活质量相关的问题，而传统的治疗方法可能很有限。这包括由于急性肾衰竭并发症引起的骨痛和透析。因此，我们认为添加新的治疗方式非常重要，包括补充剂、营养调整、针灸和身心疗法，以提高治疗耐受性、有效性和患者的生活质量。此外，许多患者自行使用其中一些补充剂，希望减少副作用，因此了解它们的作用和潜在风险更为重要。本综述的目的是说明所有这些潜在可用的策略，以丰富我们对这种迄今为止无法治愈的疾病的治疗方法。
