Department of Nursing, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
J Int Med Res. 2024 Jan;52(1):3000605231223087. doi: 10.1177/03000605231223087.
In this investigation, we aimed to explore risk factors for 90-day hospital readmission among patients with cirrhosis and ascites in an Asian population.
In this retrospective study, we included consecutive patients diagnosed with cirrhosis and ascites hospitalized in Renji Hospital between 2018 and 2022 to elucidate risk factors for 90-day readmission. We conducted multivariate logistic regression analysis to identify readmission risk factors.
We included 265 patients with cirrhosis and ascites. A 43% readmission rate was observed within 90 days. After adjustment for multiple covariates, we found that readmission within 90 days was independently linked to reduced levels of hemoglobin (odds ratio [OR] 0.96, 95% confidence interval [CI] 0.94-0.97) and serum albumin (OR 0.88, 95% CI 0.83-0.93), and higher Model for End-Stage Liver Disease and sodium (MELD-Na) scores (OR 1.04, 95% CI 1.01-1.07) at discharge.
Patients with cirrhosis who have ascites are frequently rehospitalized within 90 days after discharge. Lower hemoglobin or albumin and higher MELD-Na scores at discharge may be the main risk factors for hospital readmission.
本研究旨在探讨亚洲人群肝硬化伴腹水患者 90 天内住院再入院的危险因素。
本回顾性研究纳入了 2018 年至 2022 年期间在仁济医院住院的连续诊断为肝硬化伴腹水的患者,以阐明 90 天再入院的危险因素。我们进行了多变量逻辑回归分析以确定再入院的危险因素。
我们纳入了 265 例肝硬化伴腹水患者。在 90 天内,有 43%的患者再入院。在调整了多个协变量后,我们发现 90 天内再入院与血红蛋白水平降低(比值比 [OR] 0.96,95%置信区间 [CI] 0.94-0.97)和血清白蛋白水平降低(OR 0.88,95% CI 0.83-0.93)独立相关,而出院时的终末期肝病模型和钠(MELD-Na)评分较高(OR 1.04,95% CI 1.01-1.07)。
肝硬化伴腹水患者出院后 90 天内再次住院的情况较为常见。出院时血红蛋白或白蛋白水平较低,MELD-Na 评分较高可能是医院再入院的主要危险因素。