Skeldon Matthew, Harris David, Dent Robert, Shiau Judy Y
Division of General Internal Medicine Department of Medicine University of Saskatchewan Saskatoon Saskatchewan Canada.
LEAF Weight Management Clinic Division of Endocrinology and Metabolism University of Ottawa Ottawa Ontario Canada.
Obes Sci Pract. 2023 Oct 31;10(1):e718. doi: 10.1002/osp4.718. eCollection 2024 Feb.
Full meal replacement (FMR) Intensive Lifestyle Interventions (ILI) have been used for weight management. However, predictors of efficacy with these programs are less clear. The primary objective was to assess weight loss predictors in a community-based FMR ILI program. A secondary objective was to determine if weight loss was different between virtual and in person ILI.
This was a retrospective cohort study involving 234 patients who started the program between 1 January 2016 and 3 March 2021. In the 24-week program, patients spent 12 weeks on FMR and then transitioned back to food for the remainder, with weekly follow up with a physician and group sessions with a dietitian. Visits were in person prior to March 2020 and virtual afterward.
Patients' average age was 47.5 years (SD = 12.0) and 73.5% were female. Average weight loss was 14.3% (SD = 6.2%). There was no significant difference in weight loss between virtual and in person programs. Patients on a Glucagon-like Peptide-1 Receptor Agonist prior lost weight. Other significant associations between groups were baseline Hemoglobin AC, classes attended, as well as the age since peak weight.
Weight loss from virtual ILI was not significantly different from person ILI. More research is needed to determine how to best stratify care as virtual or in person using FMR programs.
全代餐(FMR)强化生活方式干预(ILI)已用于体重管理。然而,这些项目疗效的预测因素尚不清楚。主要目的是评估基于社区的FMR ILI项目中的体重减轻预测因素。次要目的是确定虚拟ILI和面对面ILI之间的体重减轻是否存在差异。
这是一项回顾性队列研究,涉及234名在2016年1月1日至2021年3月3日期间开始该项目的患者。在为期24周的项目中,患者在FMR上花费12周,然后在剩余时间恢复正常饮食,每周接受医生随访,并与营养师进行小组讨论。2020年3月之前的就诊是面对面的,之后是虚拟就诊。
患者的平均年龄为47.5岁(标准差=12.0),73.5%为女性。平均体重减轻14.3%(标准差=6.2%)。虚拟项目和面对面项目之间的体重减轻没有显著差异。之前使用胰高血糖素样肽-1受体激动剂的患者体重减轻。各亚组之间的其他显著关联包括基线糖化血红蛋白、参加课程的次数以及自体重峰值以来的年龄。
虚拟ILI导致的体重减轻与面对面ILI没有显著差异。需要更多研究来确定如何使用FMR项目以最佳方式将护理分层为虚拟或面对面形式。