Boutton T W, Trowbridge F L, Nelson M M, Wills C A, Smith E O, Lopez de Romana G, Madrid S, Marks J S, Klein P D
Am J Clin Nutr. 1987 Mar;45(3):513-25. doi: 10.1093/ajcn/45.3.513.
Total body water (TBW) was measured by 18O dilution in 139 undernourished, preschool Peruvian children with high weight-for-height. Values for TBW as a percent of body weight were relatively high, averaging 67.4 +/- 6.4%. Depending upon the method of calculation, mean values for the sample population for percent fat ranged from 9.4-18.5%. Regression of TBW on lean body mass suggested that hydration of the fat-free body was higher than for normally nourished children of comparable age. Thus, the increased weight-for-height in these children did not result from increased fat tissue, but from increased hydration of the fat-free body. TBW was most highly correlated with height and weight, both with r = 0.95. Equations predicting TBW from either height or weight were significantly different from those developed by other investigators to predict TBW for normal, well-nourished American children.
采用氧-18稀释法对139名身高别体重较高的秘鲁学龄前营养不良儿童进行了全身水含量（TBW）测定。TBW占体重的百分比相对较高，平均为67.4±6.4%。根据计算方法的不同，样本人群的体脂百分比平均值在9.4 - 18.5%之间。TBW与去脂体重的回归分析表明，无脂身体的水合作用高于同龄正常营养儿童。因此，这些儿童身高别体重增加并非源于脂肪组织增加，而是无脂身体水合作用增强。TBW与身高和体重的相关性最高，两者的相关系数r均为0.95。根据身高或体重预测TBW的方程与其他研究者为正常、营养良好的美国儿童预测TBW所建立的方程有显著差异。
