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经皮内镜下腰椎间盘切除术(PELD)中L4/5椎间隙靶向穿刺的稳定性模拟分析

Stability simulation analysis of targeted puncture in L4/5 intervertebral space for PELD surgery.

作者信息

Liu Yuhuai, Zhang Qiongchi, Ji Ning, Wang Jie, Li Jie, Du Jinpei, Zhao Jinghao, Ouyang Pengrong, Qin Jie, Li Haopeng, Wang Dong

机构信息

Department of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

出版信息

Front Bioeng Biotechnol. 2024 Jan 8;11:1298914. doi: 10.3389/fbioe.2023.1298914. eCollection 2023.

Abstract

The application prospects of percutaneous endoscopic lumbar discectomy (PELD) as a minimally invasive spinal surgery method in the treatment of lumbar disc herniation are extensive. This study aims to find the optimal entry angle for the trephine at the L4/5 intervertebral space, which causes less lumbar damage and has greater postoperative stability. To achieve this, we conduct a three-dimensional simulated analysis of the degree of damage caused by targeted puncture-based trephine osteotomy on the lumbar spine. We gathered clinical CT data from patients to construct a lumbar model. This model was used to simulate and analyze the variations in trephine osteotomy volume resulting from targeted punctures at the L4/5 interspace. Furthermore, according to these variations in osteotomy volume, we created Finite Element Analysis (FEA) models specifically for the trephine osteotomy procedure. We then applied mechanical loads to conduct range of motion and von Mises stress analyses on the lumbar motion unit. In percutaneous endoscopic interlaminar discectomy, the smallest osteotomy volume occurred with a 20° entry angle, close to the base of the spinous process. The volume increased at 30° and reached its largest at 40°. In percutaneous transforaminal endoscopic discectomy, the largest osteotomy volume was observed with a 50° entry angle, passing through the facet joints, with smaller volumes at 60° and the smallest at 70°. In FEA, M6 exhibited the most notable biomechanical decline, particularly during posterior extension and right rotation. M2 and M3 showed significant differences primarily in rotation, whereas the differences between M3 and M4 were most evident in posterior extension and right rotation. M5 displayed their highest stress levels primarily in posterior extension, with significant variations observed in right rotation alongside M4. The appropriate selection of entry sites can reduce lumbar damage and increase stability. We suggest employing targeted punctures at a 30° angle for PEID and at a 60° angle for PTED at the L4/5 intervertebral space. Additionally, reducing the degree of facet joint damage is crucial to enhance postoperative stability in lumbar vertebral motion units.

摘要

经皮内镜下腰椎间盘切除术(PELD)作为一种微创脊柱手术方法在治疗腰椎间盘突出症方面具有广泛的应用前景。本研究旨在寻找在L4/5椎间隙进行环锯操作的最佳进针角度,该角度能减少对腰椎的损伤并具有更高的术后稳定性。为实现这一目标,我们对基于靶向穿刺的环锯截骨术对腰椎造成的损伤程度进行三维模拟分析。我们收集患者的临床CT数据以构建腰椎模型。该模型用于模拟和分析在L4/5间隙进行靶向穿刺时环锯截骨体积的变化。此外,根据这些截骨体积的变化,我们专门为环锯截骨手术创建了有限元分析(FEA)模型。然后我们施加机械载荷对腰椎运动单元进行活动范围和冯·米塞斯应力分析。在经皮内镜下椎间孔切开椎间盘切除术(PEID)中,进针角度为20°(靠近棘突根部)时截骨体积最小,30°时体积增加,40°时达到最大。在经皮椎间孔镜下椎间盘切除术(PTED)中,进针角度为50°(穿过小关节)时观察到最大截骨体积,60°时体积较小,70°时最小。在有限元分析中,M6表现出最显著的生物力学下降,尤其是在后伸和右旋时。M2和M3主要在旋转方面存在显著差异,而M3和M4之间的差异在后伸和右旋时最为明显。M5主要在后伸时显示出最高应力水平,在右旋时与M4一起观察到显著变化。合适的进针点选择可以减少对腰椎的损伤并提高稳定性。我们建议在L4/5椎间隙进行PEID时采用30°角度的靶向穿刺,进行PTED时采用60°角度。此外,减少小关节损伤程度对于提高腰椎运动单元的术后稳定性至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c36f/10800398/3b82c59fea51/fbioe-11-1298914-g001.jpg

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