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Attenuated sodium appetite in response to sodium deficiency in Fischer-344 rats.

作者信息

Midkiff E E, Fitts D A, Simpson J B, Bernstein I L

出版信息

Am J Physiol. 1987 Mar;252(3 Pt 2):R562-6. doi: 10.1152/ajpregu.1987.252.3.R562.

DOI:10.1152/ajpregu.1987.252.3.R562
PMID:3826418
Abstract

Fischer-344 (F-344) rats avoid NaCl solutions which are preferred by other strains. The present studies examined Na appetite induced by two methods: maintenance on a Na-deficient diet, and Na depletion by injection of furosemide. In comparison with outbred Wistar rats, F-344 rats showed no evidence of Na appetite induced by Na-deficient diet after the first 15 min (study 1) and demonstrated attenuated Na appetite in response to the natriuretic effects of furosemide (study 2). Since Na loss by Wistar and F-344 rats was similar, it is likely that this reduced Na appetite was due to hedonic differences between the strains rather than to differential renal response to furosemide or Na-deficient diet.

摘要

相似文献

1
Attenuated sodium appetite in response to sodium deficiency in Fischer-344 rats.
Am J Physiol. 1987 Mar;252(3 Pt 2):R562-6. doi: 10.1152/ajpregu.1987.252.3.R562.
2
Absence of sodium chloride preference in Fischer-344 rats.
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Am J Physiol. 1995 Aug;269(2 Pt 2):R350-6. doi: 10.1152/ajpregu.1995.269.2.R350.
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Strain differences in taste reactivity to NaCl.对氯化钠味觉反应性的品系差异。
Am J Physiol. 1988 Sep;255(3 Pt 2):R424-30. doi: 10.1152/ajpregu.1988.255.3.R424.
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Selective effects of sodium and chloride depletion on salt appetite in rats.钠和氯缺乏对大鼠盐食欲的选择性影响。
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Amiloride sensitivity of chorda tympani response to NaCl in Fischer 344 and Wistar rats.Fischer 344大鼠和Wistar大鼠中鼓索神经对氯化钠反应的氨氯地平敏感性
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Sodium appetite after transection of the chorda tympani nerve in Wistar and Fischer 344 rats.
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Induction of an appetite for sodium in rats that show no spontaneous preference for sodium chloride solution--the Fischer 344 strain.在对氯化钠溶液无自发偏好的大鼠（Fischer 344品系）中诱导对钠的食欲。
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引用本文的文献

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Age-related declines in thirst and salt appetite responses in male Fischer 344×Brown Norway rats.雄性Fischer 344×Brown Norway大鼠与年龄相关的口渴和盐食欲反应下降。
Physiol Behav. 2014 Aug;135:180-8. doi: 10.1016/j.physbeh.2014.06.010. Epub 2014 Jun 19.
2
Behavioral genetics and taste.行为遗传学与味觉。
BMC Neurosci. 2007 Sep 18;8 Suppl 3(Suppl 3):S3. doi: 10.1186/1471-2202-8-S3-S3.