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揭示肠道-心脏轴:心血管健康领域的范式转变。

Unlocking the Gut-Cardiac Axis: A Paradigm Shift in Cardiovascular Health.

作者信息

Akshay Akshay, Gasim Rayan, Ali Thowaiba E, Kumar Yash Sailesh, Hassan Ahmad

机构信息

Acute Medicine, Russell Hall Hospital, Dudley, GBR.

Internal Medicine, University of Khartoum, Khartoum, SDN.

出版信息

Cureus. 2023 Dec 24;15(12):e51039. doi: 10.7759/cureus.51039. eCollection 2023 Dec.

Abstract

The gut-cardiac axis represents an emerging area of research focusing on the relationship between gut health and cardiovascular function. This narrative review examines the Gut-Cardiac Axis, emphasizing its emerging role in cardiovascular health and disease management. Traditionally viewed as a component of the digestive system, the gut is now recognized for its significant influence on cardiac health. The gut microbiota, its metabolites, and gut-related inflammation are key factors affecting heart structure and function. This review highlights how dietary and nutritional interventions can effectively modulate the gut-cardiac axis, leading to personalized strategies for optimizing cardiovascular health. We discuss the clinical relevance of the gut-cardiac axis, particularly its role in providing diagnostic and prognostic markers for cardiovascular diseases. This exploration of the gut-cardiac axis marks a significant shift in cardiology, integrating gut health into cardiovascular risk assessment and treatment strategies. The review provides an in-depth overview of current research and its potential to impact cardiovascular medicine significantly. We emphasize the importance of this research in advancing patient care and improving cardiac outcomes, underlining the potential of the gut-cardiac axis to transform cardiovascular health management.

摘要

肠-心轴是一个新兴的研究领域,专注于肠道健康与心血管功能之间的关系。本叙述性综述探讨了肠-心轴,强调了其在心血管健康和疾病管理中日益凸显的作用。传统上,肠道被视为消化系统的一个组成部分,如今它对心脏健康的重大影响已得到认可。肠道微生物群、其代谢产物以及与肠道相关的炎症是影响心脏结构和功能的关键因素。本综述重点介绍了饮食和营养干预如何有效调节肠-心轴,从而形成优化心血管健康的个性化策略。我们讨论了肠-心轴的临床相关性,尤其是其在为心血管疾病提供诊断和预后标志物方面的作用。对肠-心轴的这一探索标志着心脏病学的重大转变,即将肠道健康纳入心血管风险评估和治疗策略中。该综述对当前研究进行了深入概述,及其对心血管医学产生重大影响的潜力。我们强调这项研究在推进患者护理和改善心脏预后方面的重要性,突显了肠-心轴改变心血管健康管理的潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/62e6/10805229/9d161c0153bf/cureus-0015-00000051039-i01.jpg

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