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重度脑损伤患者的睡眠研究——多导睡眠图检查

Sleep study on patients with severe brain damage--polysomnographical examination.

作者信息

Kohyama J, Shishikura J, Nakano I, Iwakawa Y, Mori K

出版信息

Brain Dev. 1986;8(6):583-9. doi: 10.1016/s0387-7604(86)80003-1.

DOI:10.1016/s0387-7604(86)80003-1
PMID:3826549
Abstract

Polysomnograms were obtained for five severely brain damaged patients, and phasic sleep parameters-body movements (BMs) and rapid eye movements (REMs)-were examined. CT scanning of their brains demonstrated large low density areas in the bilateral hemispheres. In the three patients with flat EEG, sleep could only be classified into two stages; one with REMs[R(+)] and one without REMs[R(-)]. In the other two patients, stage R(-) was further classified into two stages according to the EEG findings. Gross movements (GMs) showed a synchronous pattern in all the patients. GMs and low angle REMs decreased in number while twitch movements and high angle REMs showed almost the same incidences as in normal controls. Localized movements showed marked variations among the patients. It was suggested that, except for normal uncoordinated asymmetrical GMs, BMs did not necessarily require higher brain structures for their generation.

摘要

对五名严重脑损伤患者进行了多导睡眠图检查,并对睡眠阶段参数——身体运动(BMs)和快速眼动(REMs)进行了检测。他们的脑部CT扫描显示双侧大脑半球有大片低密度区。在三名脑电图呈平线的患者中,睡眠只能分为两个阶段;一个有快速眼动[R(+)],一个没有快速眼动[R(-)]。在另外两名患者中,根据脑电图结果,R(-)阶段进一步分为两个阶段。所有患者的总体运动(GMs)呈现同步模式。总体运动和低角度快速眼动的数量减少,而抽搐运动和高角度快速眼动的发生率与正常对照组几乎相同。局部运动在患者之间表现出明显差异。研究表明,除了正常的不协调不对称总体运动外,身体运动的产生不一定需要更高层次的脑结构。

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