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Brake Early: RGS14 in CA2 Limits Seizures and Oxidative Stress After SE.

作者信息

Metcalf Cameron S

机构信息

Department of Pharmacology & Toxicology, University of Utah.

出版信息

Epilepsy Curr. 2023 Sep 28;23(6):372-374. doi: 10.1177/15357597231199343. eCollection 2023 Nov-Dec.

Abstract
摘要

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本文引用的文献

1
Hippocampal area CA2: interneuron disfunction during pathological states.
Front Neural Circuits. 2023 Apr 27;17:1181032. doi: 10.3389/fncir.2023.1181032. eCollection 2023.
2
RGS14 limits seizure-induced mitochondrial oxidative stress and pathology in hippocampus.
Neurobiol Dis. 2023 Jun 1;181:106128. doi: 10.1016/j.nbd.2023.106128. Epub 2023 Apr 17.
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Integration of the CA2 region in the hippocampal network during epileptogenesis.
Hippocampus. 2023 Mar;33(3):223-240. doi: 10.1002/hipo.23479. Epub 2022 Nov 24.
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Enhanced excitability of the hippocampal CA2 region and its contribution to seizure activity in a mouse model of temporal lobe epilepsy.
Neuron. 2022 Oct 5;110(19):3121-3138.e8. doi: 10.1016/j.neuron.2022.07.020. Epub 2022 Aug 19.
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RGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling.
eNeuro. 2018 Jun 4;5(3). doi: 10.1523/ENEURO.0353-17.2018. eCollection 2018 May-Jun.
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Roles for Regulator of G Protein Signaling Proteins in Synaptic Signaling and Plasticity.
Mol Pharmacol. 2016 Feb;89(2):273-86. doi: 10.1124/mol.115.102210. Epub 2015 Dec 11.
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The epileptic human hippocampal cornu ammonis 2 region generates spontaneous interictal-like activity in vitro.
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