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RIOK1 synergizes with TRIP13 by regulating the E2F-Rb signaling pathway to promote the proliferation of esophageal cancer cells.

作者信息

Li Chengyu, Pan Deyuan, Lin Wan, Deng Danxia, Zhou Yingxin, Zhao Hui, Pan Feng, Xu Liyan, Li Enmin, Long Lin

机构信息

The Key Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Department of Biochemistry and Molecular Biology, Shantou University Medical College, Shantou, Guangdong 515041, China.

Guangdong Provincial Key Laboratory of Infectious Diseases and Molecular Immunopathology, Institute of Oncologic Pathology, Shantou University Medical College, Shantou, Guangdong 515041, China.

出版信息

Genes Dis. 2023 Jun 24;11(3):100990. doi: 10.1016/j.gendis.2023.04.024. eCollection 2024 May.

DOI:10.1016/j.gendis.2023.04.024
PMID:38274384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10808919/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/9e56af594b70/figs8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/936b736af813/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/eacb7b0c3fa9/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/8f53aa6d3852/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/7a41b581f748/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/e2c43117682d/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/b3e8738a3eb8/figs5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/a22b203ff44a/figs6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/f4cabd872c92/figs7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/9e56af594b70/figs8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/936b736af813/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/eacb7b0c3fa9/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/8f53aa6d3852/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/7a41b581f748/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/e2c43117682d/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/b3e8738a3eb8/figs5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/a22b203ff44a/figs6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/f4cabd872c92/figs7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24b8/10808919/9e56af594b70/figs8.jpg

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本文引用的文献

1
Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting.基于大规模和高分辨率质谱的蛋白质组学分析为治疗靶点定义了食管癌的分子亚型。
Nat Commun. 2021 Aug 16;12(1):4961. doi: 10.1038/s41467-021-25202-5.
2
TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.TRIP13损害有丝分裂检查点监测，与多发性骨髓瘤的不良预后相关。
Oncotarget. 2017 Apr 18;8(16):26718-26731. doi: 10.18632/oncotarget.14957.
3
Pch2(TRIP13): controlling cell division through regulation of HORMA domains.
Pch2（TRIP13）：通过调控HORMA结构域来控制细胞分裂。
Chromosoma. 2015 Sep;124(3):333-9. doi: 10.1007/s00412-015-0516-y. Epub 2015 Apr 21.
4
Oesophageal carcinoma.食管癌。
Lancet. 2013 Feb 2;381(9864):400-12. doi: 10.1016/S0140-6736(12)60643-6.
5
Cancer trends in China.中国癌症趋势。
Jpn J Clin Oncol. 2010 Apr;40(4):281-5. doi: 10.1093/jjco/hyp187. Epub 2010 Jan 18.