Michel C C
Acta Physiol Scand Suppl. 1979;463:67-74.
Measurements of filtration coefficients (Lp) and osmotic reflexion coefficients (sigma) of single capillaries in the frog mesentery suggest that fluid flows through the walls of these vessels in two types of channel. One channel type (representing about 10% of Lp) appears to be exclusively available for water whereas the other channels appear available for both water and hydrophilic solutes though they severely restrict the passage of albumin (sigma = 0.81). The effects of proteins in the perfusate upon Lp and studies on the passage of ferritin into the surface vesicles of the endothelial cells, suggest that an important component of capillary permeability may reside in an endocapillary layer.
对蛙肠系膜中单个毛细血管的滤过系数（Lp）和渗透反射系数（sigma）的测量表明，液体通过这些血管壁有两种通道类型。一种通道类型（约占Lp的10%）似乎仅允许水通过，而其他通道似乎对水和亲水性溶质都开放，尽管它们严重限制白蛋白的通过（sigma = 0.81）。灌注液中蛋白质对Lp的影响以及铁蛋白进入内皮细胞表面囊泡的研究表明，毛细血管通透性的一个重要组成部分可能存在于毛细血管内皮层。
