微生物与乳腺癌：临床研究的深入分析
Microorganisms and Breast Cancer: An In-Depth Analysis of Clinical Studies.
作者信息
Naderi Naghmeh, Mosahebi Afshin, Williams Norman R
机构信息
Department of Plastic and Reconstructive Surgery, Royal Free Hospital, London NW3 2QG, UK.
Division of Surgery & Interventional Science, University College London, London W1W 7TY, UK.
出版信息
Pathogens. 2023 Dec 19;13(1):6. doi: 10.3390/pathogens13010006.
Breast cancer is a multifactorial disease that affects millions of women worldwide. Recent work has shown intriguing connections between microorganisms and breast cancer, which might have implications for prevention and treatment. This article analyzed 117 relevant breast cancer clinical studies listed on ClinicalTrials.gov selected using a bespoke set of 38 search terms focused on bacteria, viruses, and fungi. This was supplemented with 20 studies found from a search of PubMed. The resulting 137 studies were described by their characteristics such as geographic distribution, interventions used, start date and status, etc. The studies were then collated into thematic groups for a descriptive analysis to identify knowledge gaps and emerging trends.
乳腺癌是一种多因素疾病，影响着全球数百万女性。最近的研究表明，微生物与乳腺癌之间存在着有趣的联系，这可能对预防和治疗具有重要意义。本文分析了ClinicalTrials.gov上列出的117项相关乳腺癌临床研究，这些研究是使用一组定制的38个搜索词筛选出来的，这些搜索词聚焦于细菌、病毒和真菌。此外，通过搜索PubMed又补充了20项研究。对这137项研究按照其地理分布、所采用的干预措施、开始日期和状态等特征进行了描述。然后将这些研究整理成不同的主题组进行描述性分析，以找出知识空白和新出现的趋势。
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