Li S C, Kundu S K, Degasperi R, Li Y T
Biochem J. 1986 Dec 15;240(3):925-7. doi: 10.1042/bj2400925.
Analysis of the glycosphingolipid composition in one case of uterine leiomyosarcoma metastasized to the liver showed an accumulation of globotriaosylceramide as compared with normal liver and uterus from which the tumour originated. The structure and the amount of glycosphingolipids were established by using specific glycosidases, permethylation analysis and h.p.l.c. The reason for the accumulation of globotriaosylceramide in leiomyosarcoma remains to be answered.
对一例转移至肝脏的子宫平滑肌肉瘤的糖鞘脂成分分析显示，与肿瘤起源的正常肝脏和子宫相比，存在球三糖神经酰胺的蓄积。通过使用特异性糖苷酶、全甲基化分析和高效液相色谱法确定了糖鞘脂的结构和含量。子宫平滑肌肉瘤中球三糖神经酰胺蓄积的原因尚待解答。
