Batume Charles, Mulongo Ivan Mugeni, Ludlow Richard, Ssebaale John, Randerson Peter, Pickett John A, Mukisa Ivan M, Scofield Simon
Department of Entomology, Uganda Virus Research Institute (UVRI), Entebbe, Uganda.
Vector Genetics Laboratory, University of California Davis, Davis, CA, USA.
Sci Rep. 2024 Jan 27;14(1):2269. doi: 10.1038/s41598-024-52715-y.
The mosquito species Aedes aegypti (L.) is known to act as a vector in the transmission of various diseases, including dengue fever and yellow fever. The use of insect repellents is one of precautionary measures used to mitigate the risk of these diseases in humans by reducing mosquito biting. Nepetalactone, a potent natural insect repellent primarily found in catnip (Nepeta cataria) essential oil, has emerged as a promising candidate for mosquito repellence. Here, we evaluated the potential of catnip essential oil (> 95% nepetalactone) for use as a mosquito repellent. Using a Y-tube olfactometer and human hands as an attractant, we analysed the effectiveness of catnip oil at repelling the mosquito species Aedes aegypti. We tested a range of dilutions of catnip essential oil and found that concentrations as low as 2% were effective at repelling > 70% of mosquitoes for between one and four hours after repellent application. These findings suggest that nepetalactone could potentially be used as a natural, effective alternative to synthetic mosquito repellents, thereby offering protection against vector-borne diseases.
埃及伊蚊(Aedes aegypti (L.))是已知的多种疾病传播媒介,包括登革热和黄热病。使用驱虫剂是通过减少蚊虫叮咬来降低人类感染这些疾病风险的预防措施之一。荆芥内酯是一种主要存在于猫薄荷(Nepeta cataria)精油中的强效天然驱虫剂,已成为一种有前景的驱蚊候选物。在此,我们评估了猫薄荷精油(荆芥内酯含量>95%)用作驱蚊剂的潜力。使用Y型嗅觉仪并以人手作为引诱源,我们分析了猫薄荷油对埃及伊蚊的驱避效果。我们测试了一系列猫薄荷精油稀释液,发现低至2%的浓度在涂抹驱虫剂后的一到四小时内对超过70%的蚊子具有驱避效果。这些发现表明,荆芥内酯有可能作为合成驱蚊剂的天然有效替代品,从而提供针对媒介传播疾病的防护。