• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用皮下保存的自体骨移植进行两阶段后-前-后手术治疗成人脊柱畸形的有效性:一项回顾性观察研究。

Effectiveness of a two-stage posterior-anterior-posterior surgery using subcutaneously preserved autologous bone grafts for adult spinal deformity: a retrospective observational study.

作者信息

Kimura Atsushi, Shiraishi Yasuyuki, Sawamura Hideaki, Inoue Hirokazu, Takeshita Katsushi

机构信息

Department of Orthopaedic Surgery, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.

出版信息

J Orthop Surg Res. 2024 Jan 27;19(1):91. doi: 10.1186/s13018-024-04572-8.

DOI:10.1186/s13018-024-04572-8
PMID:38281002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10821239/
Abstract

BACKGROUND

To achieve optimal correction of rigid kyphoscoliosis, we developed a novel two-stage posterior-anterior-posterior (PAP) surgery using subcutaneously preserved autologous bone grafts. This study aimed to investigate the effectiveness of two-stage PAP surgery versus single-stage anterior-posterior (AP) surgery.

METHODS

This was a retrospective analysis of patients undergoing combined anterior-posterior long-level fusion for adult spinal deformity (ASD) with a minimum 2-year follow-up. The indications for two-stage PAP surgery were rigid thoracolumbar deformity associated with hypertrophic facet arthritis and/or a large pelvic incidence-lumbar lordosis mismatch of > 25°. In the first stage of PAP surgery, pedicle screw insertion and multilevel Ponte osteotomies were performed. The resected local bone was embedded under sutured fascia. One week later, the embedded bone was retrieved in the right lateral position and used as an autograft for lateral lumbar interbody fusion. Final deformity correction was performed in the prone position.

RESULTS

From January 2018 to April 2021, 12 and 16 patients with ASD underwent two-stage PAP surgery (PAP group) and single-stage AP surgery (AP group), respectively. Although PAP surgery was associated with a significantly longer operation time, the total blood loss volume was significantly less in the PAP group than the AP group. Compared with the AP group, the PAP group showed significantly larger postoperative changes in radiological parameters in the sagittal and coronal planes. The overall complication rate did not differ significantly between the two groups.

CONCLUSION

Two-stage PAP surgery provided effective correction of rigid kyphoscoliosis without increasing blood loss and postoperative complication rates.

摘要

背景

为实现对僵硬性脊柱侧凸的最佳矫正,我们开发了一种新型的两阶段前后后(PAP)手术,使用皮下保存的自体骨移植。本研究旨在探讨两阶段PAP手术与单阶段前后(AP)手术的有效性。

方法

这是一项对接受成人脊柱畸形(ASD)前后联合长节段融合且至少随访2年的患者的回顾性分析。两阶段PAP手术的适应证为与肥厚性小关节关节炎相关的僵硬性胸腰段畸形和/或骨盆入射角与腰椎前凸失配大于25°。在PAP手术的第一阶段,进行椎弓根螺钉置入和多节段庞特截骨术。切除的局部骨埋置于缝合的筋膜下。一周后,在右侧卧位取出埋置的骨并用作腰椎椎间融合的自体移植物。最终的畸形矫正在俯卧位进行。

结果

2018年1月至2021年4月,分别有12例和16例ASD患者接受了两阶段PAP手术(PAP组)和单阶段AP手术(AP组)。尽管PAP手术的手术时间明显更长,但PAP组的总失血量明显少于AP组。与AP组相比,PAP组在矢状面和冠状面的放射学参数术后变化明显更大。两组的总体并发症发生率无显著差异。

结论

两阶段PAP手术可有效矫正僵硬性脊柱侧凸,且不增加失血量和术后并发症发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/dca2f9405bff/13018_2024_4572_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/6565d8b67a0f/13018_2024_4572_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/a0781754abf7/13018_2024_4572_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/3dfb0fe72b25/13018_2024_4572_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/dca2f9405bff/13018_2024_4572_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/6565d8b67a0f/13018_2024_4572_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/a0781754abf7/13018_2024_4572_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/3dfb0fe72b25/13018_2024_4572_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f1e/10821239/dca2f9405bff/13018_2024_4572_Fig4_HTML.jpg

相似文献

1
Effectiveness of a two-stage posterior-anterior-posterior surgery using subcutaneously preserved autologous bone grafts for adult spinal deformity: a retrospective observational study.使用皮下保存的自体骨移植进行两阶段后-前-后手术治疗成人脊柱畸形的有效性:一项回顾性观察研究。
J Orthop Surg Res. 2024 Jan 27;19(1):91. doi: 10.1186/s13018-024-04572-8.
2
Comparative analysis of 3 surgical strategies for adult spinal deformity with mild to moderate sagittal imbalance.成人脊柱畸形伴轻至中度矢状面失衡的三种手术策略的比较分析
J Neurosurg Spine. 2018 Jan;28(1):40-49. doi: 10.3171/2017.5.SPINE161370. Epub 2017 Nov 3.
3
Posterior corrective surgery with a multilevel transforaminal lumbar interbody fusion and a rod rotation maneuver for patients with degenerative lumbar kyphoscoliosis.采用多级经椎间孔腰椎椎间融合术及棒旋转操作对退变性腰椎后凸侧弯患者进行后路矫正手术。
J Neurosurg Spine. 2017 Feb;26(2):150-157. doi: 10.3171/2016.7.SPINE16172. Epub 2016 Oct 7.
4
Utility of multilevel lateral interbody fusion of the thoracolumbar coronal curve apex in adult deformity surgery in combination with open posterior instrumentation and L5-S1 interbody fusion: a case-matched evaluation of 32 patients.胸腰段冠状面弯曲顶点多级外侧椎间融合术在成人脊柱畸形手术中联合开放后路内固定及L5-S1椎间融合的效用:32例病例匹配评估
J Neurosurg Spine. 2017 Feb;26(2):208-219. doi: 10.3171/2016.8.SPINE151543. Epub 2016 Oct 21.
5
Mini-open pedicle subtraction osteotomy as a treatment for severe adult spinal deformities: case series with initial clinical and radiographic outcomes.微创开放椎弓根截骨术治疗重度成人脊柱畸形:初步临床及影像学结果的病例系列研究
J Neurosurg Spine. 2016 May;24(5):769-76. doi: 10.3171/2015.7.SPINE15188. Epub 2016 Jan 8.
6
Posterior-approach single-level apical spinal osteotomy in pediatric patients for severe rigid kyphoscoliosis: long-term clinical and radiological outcomes.小儿严重僵硬型脊柱侧凸患者后路单节段顶椎截骨术:长期临床和影像学结果
J Neurosurg Pediatr. 2018 Jun;21(6):606-614. doi: 10.3171/2017.12.PEDS17404. Epub 2018 Mar 30.
7
Posterior all-pedicle screw instrumentation combined with multiple chevron and concave rib osteotomies in the treatment of adolescent congenital kyphoscoliosis.后路全椎弓根螺钉内固定联合多节段楔形截骨和凹侧楔形截骨矫形术治疗青少年先天性脊柱后凸侧凸畸形。
Spine J. 2014 Jan;14(1):11-9. doi: 10.1016/j.spinee.2012.10.016. Epub 2012 Dec 4.
8
A 10-Year Radiographic Study Comparing Anterior Versus Posterior Instrumented Spinal Fusion in Patients With Lenke Type 5 Adolescent Idiopathic Scoliosis.一项比较 Lenke 型 5 型青少年特发性脊柱侧凸患者前路与后路器械性脊柱融合的 10 年影像学研究。
Spine (Phila Pa 1976). 2020 May 1;45(9):612-620. doi: 10.1097/BRS.0000000000003331.
9
The feasibility of computer-assisted 3D navigation in multiple-level lateral lumbar interbody fusion in combination with posterior instrumentation for adult spinal deformity.计算机辅助三维导航在成人脊柱畸形后路内固定联合多节段侧路腰椎间融合术中的可行性。
Neurosurg Focus. 2020 Sep;49(3):E4. doi: 10.3171/2020.5.FOCUS20353.
10
Comparative study of multilevel posterior interbody fusion plus anterior longitudinal ligament release versus classic multilevel posterior interbody fusion in the treatment of adult spinal deformities.后路多节段椎体间融合加前纵韧带松解与经典后路多节段椎体间融合治疗成人脊柱畸形的对比研究。
J Neurosurg Spine. 2019 Apr 5;31(1):46-52. doi: 10.3171/2019.1.SPINE18754. Print 2019 Jul 1.

引用本文的文献

1
Comparative analysis of single-stage versus two-stage fusion surgeries for adult spinal deformity: radiographic outcomes, clinical improvements, and complication rates.成人脊柱畸形单阶段与两阶段融合手术的比较分析:影像学结果、临床改善及并发症发生率
Eur Spine J. 2025 Jun 11. doi: 10.1007/s00586-025-09036-z.

本文引用的文献

1
Combined anterior-posterior versus all-posterior approaches for adult spinal deformity correction: a matched control study.前后联合入路与全后路入路治疗成人脊柱畸形的对比:一项配对对照研究。
Eur Spine J. 2022 Jul;31(7):1754-1764. doi: 10.1007/s00586-022-07249-0. Epub 2022 May 27.
2
Risk factors for intraoperative endplate injury during minimally-invasive lateral lumbar interbody fusion.微创侧方腰椎椎间融合术中终板损伤的危险因素。
Sci Rep. 2021 Oct 11;11(1):20149. doi: 10.1038/s41598-021-99751-6.
3
Planned two-stage surgery using lateral lumbar interbody fusion and posterior corrective fusion: a retrospective study of perioperative complications.
采用侧路腰椎椎间融合与后路矫形融合的计划性两阶段手术:围手术期并发症的回顾性研究。
Eur Spine J. 2021 Aug;30(8):2368-2376. doi: 10.1007/s00586-021-06879-0. Epub 2021 May 27.
4
Marked Increase in Spinal Deformity Surgery Throughout the United States.美国脊柱畸形手术显著增加。
Spine (Phila Pa 1976). 2021 Oct 15;46(20):1402-1408. doi: 10.1097/BRS.0000000000004041.
5
Controlled Multifactorial Coagulopathy: Effects of Dilution, Hypothermia, and Acidosis on Thrombin Generation In Vitro.控制性多因素凝血障碍:稀释、低温和酸中毒对体外凝血酶生成的影响。
Anesth Analg. 2020 Apr;130(4):1063-1076. doi: 10.1213/ANE.0000000000004479.
6
Changes in Spinal Alignment following eXtreme Lateral Interbody Fusion Alone in Patients with Adult Spinal Deformity using Computed Tomography.单纯使用计算机断层扫描的极外侧椎间融合术治疗成人脊柱畸形后脊柱对线的变化。
Sci Rep. 2019 Aug 19;9(1):12039. doi: 10.1038/s41598-019-48539-w.
7
Should Surgery for Adult Degenerative Lumbar Deformity be Staged?成人退变性腰椎畸形手术应该分期进行吗?
Clin Spine Surg. 2019 Aug;32(7):269-271. doi: 10.1097/BSD.0000000000000775.
8
Comparative analysis of 3 surgical strategies for adult spinal deformity with mild to moderate sagittal imbalance.成人脊柱畸形伴轻至中度矢状面失衡的三种手术策略的比较分析
J Neurosurg Spine. 2018 Jan;28(1):40-49. doi: 10.3171/2017.5.SPINE161370. Epub 2017 Nov 3.
9
Under Correction of Sagittal Deformities Based on Age-adjusted Alignment Thresholds Leads to Worse Health-related Quality of Life Whereas Over Correction Provides No Additional Benefit.基于年龄调整的对线阈值来矫正矢状位畸形会导致健康相关生活质量更差,而过矫则没有额外获益。
Spine (Phila Pa 1976). 2018 Mar 15;43(6):388-393. doi: 10.1097/BRS.0000000000002435.
10
Predisposing Factors for Intraoperative Endplate Injury of Extreme Lateral Interbody Fusion.极外侧椎间融合术中终板损伤的易感因素
Asian Spine J. 2016 Oct;10(5):907-914. doi: 10.4184/asj.2016.10.5.907. Epub 2016 Oct 17.