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特应性皮炎护肤品中主要食物过敏原的患病率。

Prevalence of major food allergens in skincare products for atopic dermatitis.

作者信息

Ryczaj Klaudia, Chojnowska-Wójtowicz Magdalena, Dumycz Karolina, Feleszko Wojciech, Kulus Marek

机构信息

Department of Paediatric Pneumonology and Allergy, Medical University of Warsaw, Warsaw, Poland.

Doctoral School, Medical University of Warsaw, Warsaw, Poland.

出版信息

Postepy Dermatol Alergol. 2023 Dec;40(6):762-765. doi: 10.5114/ada.2023.133819. Epub 2024 Jan 8.

Abstract

INTRODUCTION

Food allergy is a common concomitant disease in patients with atopic dermatitis. Sensitisation and subsequent development of food allergy might result from the application of skincare products containing food allergens, particularly when the skin barrier is impaired and inflamed. Emollients are the mainstay of the management of atopic dermatitis; however, the prevalence of food allergens in skincare products used for atopic dermatitis is unknown.

AIM

To analyse the prevalence of major food allergens in skincare products for atopic dermatitis.

MATERIAL AND METHODS

Three major online cosmetic retailers in Poland were screened for atopic skincare products. The major food allergens under the mandatory allergen labelling regulation of the European Union were searched for using the INCI nomenclature of cosmetics ingredients.

RESULTS

We screened 396 skincare products, out of which 127 (32.1%) products contained at least one derivative of a major food allergen. The most common allergens were almonds, macadamia nuts, soya and cereals, followed by sesame and milk. There was no significant difference in the presence of food derivatives between leave-on and rinse-off skincare products, as well as between those intended for use by infants and children, and adults only.

CONCLUSIONS

Our analysis revealed that major food allergens are prevalent in skincare products for eczema. Applying skincare products containing food derivatives on affected and inflamed skin can promote percutaneous sensitisation. Therefore, clinicians and patients with atopic dermatitis must be careful of products used for treating eczema that may contain derivatives of a major food allergen.

摘要

引言

食物过敏是特应性皮炎患者常见的伴发疾病。使用含有食物过敏原的护肤品可能导致致敏以及随后食物过敏的发生,尤其是当皮肤屏障受损且发炎时。润肤剂是特应性皮炎治疗的主要手段;然而,用于特应性皮炎的护肤品中食物过敏原的患病率尚不清楚。

目的

分析用于特应性皮炎的护肤品中主要食物过敏原的患病率。

材料与方法

对波兰三家主要的在线化妆品零售商销售的特应性护肤品进行筛选。使用化妆品成分的国际化妆品原料命名法搜索欧盟强制性过敏原标签法规规定的主要食物过敏原。

结果

我们筛选了396种护肤品,其中127种(32.1%)产品含有至少一种主要食物过敏原的衍生物。最常见的过敏原是杏仁、澳洲坚果、大豆和谷物,其次是芝麻和牛奶。免洗型和冲洗型护肤品之间,以及仅供婴儿和儿童使用的产品与仅供成人使用的产品之间,食物衍生物的存在没有显著差异。

结论

我们的分析表明,主要食物过敏原在用于湿疹的护肤品中普遍存在。在受影响且发炎的皮肤上使用含有食物衍生物的护肤品会促进经皮致敏。因此,临床医生和特应性皮炎患者必须小心用于治疗湿疹的可能含有主要食物过敏原衍生物的产品。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9aee/10809837/399ebfd1b591/PDIA-40-52084-g001.jpg

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