Gómez-Verduzco Gabriela, Arce-Menocal José, López-Coello Carlos, Avila-González Ernesto, Márquez-Mota Claudia C, Polo Javier, Rangel Luis
Departamento de Medicina y Zootecnia de Aves, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autónoma de México, Ciudad de México, Mexico.
Departamento de Producción avícola, Facultad de Medicina Veterinaria y Zootecnia, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Mexico.
Front Vet Sci. 2024 Jan 11;10:1321351. doi: 10.3389/fvets.2023.1321351. eCollection 2023.
Fungi that produce mycotoxins can grow on certain food products, such as grains and feed, and can cause a variety of health issues if consumed by animals, including chickens. The use of spray-dried plasma (SDP) is one strategy for combating the health problems caused by mycotoxins.
In the present study, Ross 308 chickens ( = 960) were divided into four treatment groups. T1 group was given a control diet (corn-soybean meal), T2 group was given a control diet +2% SDP, T3 group was given a control diet +2% SDP + mixture mycotoxins and T4 group was givena control diet + mycotoxin mixture.
The presence of SDP resulted in weight gain and decreased feed efficiency, whereas mycotoxins resulted in weight loss and increased feed efficiency. SDP increased the thymus' relative weight. The presence of mycotoxins increased the heterophile/lymphocyte ratio. The presence of mycotoxins reduced the production of IL-2 and macrophage inflammatory protein-3 Alpha (MIP-3a), whereas the presence of SDP increased the production of macrophage colony-stimulating Factor (M-CSF). SDP resulted in higher IgA concentrations in the intestinal and tracheal washes than mycotoxin. Finally, adding SDP to broiler diets boosts weight gain, feed efficiency, and immune system development.
Our results provide information supporting that SDP is a promising tool for improving poultry immunity and performance.
产生霉菌毒素的真菌可在某些食品上生长，如谷物和饲料，若被包括鸡在内的动物食用，会引发多种健康问题。使用喷雾干燥血浆（SDP）是对抗霉菌毒素所致健康问题的一种策略。
在本研究中，960只罗斯308肉鸡被分为四个处理组。T1组给予对照日粮（玉米 - 豆粕），T2组给予对照日粮 + 2% SDP，T3组给予对照日粮 + 2% SDP + 混合霉菌毒素，T4组给予对照日粮 + 霉菌毒素混合物。
SDP的存在导致体重增加和饲料效率降低，而霉菌毒素导致体重减轻和饲料效率提高。SDP增加了胸腺的相对重量。霉菌毒素的存在增加了嗜异性粒细胞/淋巴细胞比率。霉菌毒素的存在降低了白细胞介素 - 2（IL - 2）和巨噬细胞炎性蛋白 - 3α（MIP - 3α）的产生，而SDP的存在增加了巨噬细胞集落刺激因子（M - CSF）的产生。SDP导致肠道和气管冲洗液中的IgA浓度高于霉菌毒素。最后，在肉鸡日粮中添加SDP可促进体重增加、饲料效率和免疫系统发育。
我们的结果提供了支持SDP是改善家禽免疫力和性能的有前景工具的信息。
