Mohamed Hassan T, Farhan Alenezi Wail Abdullah, Alanzi Muhannad Abdullah A, Saleh Alsuqub Faris Ibrahim, Salem Alhazmi Salem Ali, Mohammed Alhazmi Omar Madhi
Pediatrics, Maternity and Children Hospital, Arar, SAU.
Pediatric Medicine, Northern Border University, Arar, SAU.
Cureus. 2023 Dec 28;15(12):e51230. doi: 10.7759/cureus.51230. eCollection 2023 Dec.
Ventilator-associated pneumonia (VAP) is a common healthcare-associated disease in intensive care units, leading to significant morbidity and mortality. This systematic review aims to investigate the prevalence, risk factors, and prevention strategies for VAP in the Middle East. PubMed, SCOPUS, Web of Science, Science Direct, and Google Scholar were systematically searched to include the relevant literature. Rayyan QCRI was used throughout this systematic approach. Ten studies, involving a total of 6295 patients diagnosed with VAP, were included in this review. Among these patients, 336 (5.3%) developed VAP. The prevalence of VAP in children and neonates in the Middle East was relatively low. Risk factors associated with VAP development included prematurity, low birth weight, prolonged mechanical ventilation, enteral feeding, intrusive devices such as umbilical catheters, and cardiac operations. All reviewed studies emphasized the importance of infection control measures in reducing the risk of VAP.
呼吸机相关性肺炎（VAP）是重症监护病房中常见的医疗相关疾病，会导致显著的发病率和死亡率。本系统评价旨在调查中东地区VAP的患病率、危险因素及预防策略。通过对PubMed、SCOPUS、Web of Science、Science Direct和谷歌学术进行系统检索，以纳入相关文献。在整个系统评价过程中使用了Rayyan QCRI。本评价纳入了10项研究，共涉及6295例诊断为VAP的患者。在这些患者中，有336例（5.3%）发生了VAP。中东地区儿童和新生儿VAP的患病率相对较低。与VAP发生相关的危险因素包括早产、低出生体重、机械通气时间延长、肠内喂养、侵入性装置（如脐静脉导管）以及心脏手术。所有纳入评价的研究均强调了感染控制措施在降低VAP风险方面的重要性。
