Kantzou Ioanna, Sarris Georgios, Kouloulias Vasileios, Abatzoglou Ioannis, Leivaditis Vasileios, Grapatsas Konstantinos, Koletsis Efstratios, Papatriantafyllou Athanasios, Dahm Manfred, Mulita Admir, Mulita Francesk, Baltayiannis Nikolaos
First Department of Radiotherapy, 'Metaxa' Cancer Hospital, Piraeus, Greece.
Second Department of Radiology, 'Attikon' University Hospital, Athens, Greece.
Kardiochir Torakochirurgia Pol. 2023 Dec;20(4):255-262. doi: 10.5114/kitp.2023.134132. Epub 2024 Jan 11.
Mediastinal tumors encompass a diverse range of malignancies, originating within or spreading to the mediastinum. The administration of radiotherapy within the anatomical confines of the mediastinum presents unique challenges owing to the close proximity of critical organs, including the heart, lungs, esophagus, and spinal cord. However, recent progress in imaging techniques, treatment modalities, and our understanding of tumor biology has significantly contributed to the development of effective and safe therapeutic strategies for mediastinal diseases. This review article aims to explore the latest innovations in radiotherapy and their practical applications in the management of mediastinal tumors, with a primary focus on lymphomas, thymomas, and thymic carcinomas. By examining these advancements, we seek to provide valuable insights into the current state of the art in radiotherapy for mediastinal malignancies, ultimately fostering improved patient outcomes and clinical decision-making.
纵隔肿瘤包括多种恶性肿瘤，起源于纵隔内或扩散至纵隔。由于纵隔内关键器官（包括心脏、肺、食管和脊髓）位置相邻，在纵隔的解剖范围内进行放射治疗面临独特挑战。然而，成像技术、治疗方式以及我们对肿瘤生物学的理解方面的最新进展，显著推动了纵隔疾病有效且安全治疗策略的发展。这篇综述文章旨在探讨放射治疗的最新创新及其在纵隔肿瘤管理中的实际应用，主要关注淋巴瘤、胸腺瘤和胸腺癌。通过研究这些进展，我们旨在为纵隔恶性肿瘤放射治疗的当前技术水平提供有价值的见解，最终促进患者预后的改善和临床决策。
