Shennan D B, Boyd C A
Biosci Rep. 1986 Oct;6(10):889-94. doi: 10.1007/BF01116242.
Sulphate efflux from human placental microvillus membrane vesicles was inhibited by external DIDS (KI congruent to 10(-6) M). This inhibition was partially reversed on addition of the translocated substrates sulphate or selenate to the external medium: selenite which is not translocated does not protect against DIDS inhibition. These findings show that the mechanism responsible for sulphate efflux can be modified by substrate in the external medium.
人胎盘微绒毛膜囊泡的硫酸盐外流受到细胞外DIDS（抑制常数约为10⁻⁶ M）的抑制。当向细胞外培养基中添加易位底物硫酸盐或硒酸盐时，这种抑制作用会部分逆转：不能易位的亚硒酸盐不能防止DIDS的抑制作用。这些发现表明，负责硫酸盐外流的机制可被细胞外培养基中的底物所改变。
