Erlandsson S, Ringdahl A, Hutchins T, Carlsson S G
Br J Audiol. 1987 Feb;21(1):37-44. doi: 10.3109/03005368709077773.
Seventeen out of 21 patients with severe tinnitus rated their tinnitus intensity during a baseline period, during treatment with a portable masker, and during a period with a comparable placebo apparatus. Group analyses showed no significant differences between any of the three periods. Seven patients showed significantly reduced tinnitus intensity ratings during the masker period; five of them also did so during the placebo treatment. After each of the treatment periods, the 21 patients answered a questionnaire about specific (tinnitus related) and general beneficial effects experienced during treatment. Specific, but not general, effects were more pronounced during masker than during placebo treatment. In conclusion, masker treatment is not unequivocally superior to placebo; there is some evidence, however, for the placebo treatment effects to be more 'nonspecific' than effects observed during masker treatment.
21例重度耳鸣患者中有17例在基线期、使用便携式掩蔽器治疗期间以及使用类似安慰剂装置期间对耳鸣强度进行了评分。组间分析显示，这三个时期中的任何两个时期之间均无显著差异。7例患者在掩蔽器治疗期间耳鸣强度评分显著降低；其中5例在安慰剂治疗期间也有此现象。在每个治疗期结束后，21例患者回答了一份关于治疗期间所体验到的特定（与耳鸣相关）和一般有益效果的问卷。与安慰剂治疗相比，掩蔽器治疗期间特定效果（而非一般效果）更为明显。总之，掩蔽器治疗并不明确优于安慰剂；然而，有一些证据表明，安慰剂治疗效果比掩蔽器治疗期间观察到的效果更具“非特异性”。
