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赞比亚卢萨卡查瓦马一级医院 15 岁及以上结核病患者的结核病治疗结局相关因素。

Factors associated with tuberculosis treatment outcomes among TB patients aged 15 years and older at chawama level one hospital in Lusaka, Zambia.

机构信息

Health Programs Department, Churches Health Association of Zambia, Lusaka, Zambia.

Department of public health school of medicine and health sciences, University of Lusaka, Lusaka, Zambia.

出版信息

Glob Public Health. 2024 Jan;19(1):2307979. doi: 10.1080/17441692.2024.2307979. Epub 2024 Jan 29.

DOI:10.1080/17441692.2024.2307979
PMID:38286134
Abstract

Tuberculosis is a global health concern n impacting communities, health systems, and economies This study assessed the TB treatment outcomes among individuals aged 15+ at Chawama first level hospital in Lusaka, Zambia, using a retrospective design focussing on individuals notified in 2020. The sample was described using descriptive statistics. The Pearson Chi-square test and logistics regression were used to analyse the characteristics of the patients influencing the treatment outcomes at 5% significant level. Out of 404 participants, 83.4% of them had successful treatment outcomes. Varied outcomes were noted in sex, patient type, TB type, HIV status, and DOT plan, but lacked significance. Odds of success were lower by 72.4% for those aged 65+ compared to those aged 15-24 years Similarly, after adjusting for other variables, the odds of success were lower by 72.9% . This study yielded an encouraging 83.4% TB success rate highlighting the potential for improvement to meet WHO targets. Notably, individuals aged 65+ showed a distinct pattern with lower treatment success odds, suggesting a need for focussed interventions. Special attention to elderly patients and targeted TB program interventions are recommended.

摘要

结核病是一个全球性的卫生问题,影响着社区、卫生系统和经济。本研究使用回顾性设计,重点关注 2020 年通报的病例,评估了赞比亚卢萨卡 Chawama 一级医院 15 岁及以上个体的结核病治疗结果。使用描述性统计对样本进行描述。使用 Pearson Chi-square 检验和逻辑回归分析在 5%的显著水平上影响治疗结果的患者特征。在 404 名参与者中,83.4%的人治疗结果成功。在性别、患者类型、结核病类型、艾滋病毒状况和直接观察治疗方案方面,结果存在差异,但缺乏显著性。与 15-24 岁年龄组相比,65 岁及以上年龄组的成功几率低 72.4%。同样,在调整其他变量后,成功的几率低 72.9%。这项研究取得了令人鼓舞的 83.4%的结核病成功率,这表明有可能改善以达到世卫组织的目标。值得注意的是,65 岁及以上的个体表现出明显的治疗成功率较低的模式,表明需要有针对性的干预措施。建议特别关注老年患者和有针对性的结核病规划干预措施。

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