Choi Sangchun, Kim Gi Woon, Lim Hoon
Department of Emergency Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea.
Clin Exp Emerg Med. 2024 Dec;11(4):335-348. doi: 10.15441/ceem.23.167. Epub 2024 Jan 29.
Following the 2011 ban on paraquat sales, Korea has witnessed a significant reduction in the mortality rate associated with acute pesticide poisoning. Traditionally, paraquat and diquat, alongside several highly toxic organophosphates, carbamates, and organochlorine insecticides, have been recognized as culprits in causing fatalities among patients with acute pesticide poisoning. However, despite global efforts to curtail the use of these highly toxic pesticides, certain pesticides still exhibit a level of lethality surpassing their established clinical toxicity profiles. Understanding the clinical progression of these pesticides is paramount for physicians and toxicologists, as it holds the potential to enhance patient prognoses in cases of acute poisoning. This review aims to address the persistence of such highly lethal pesticides, which continue to pose a grave threat to victims of acute poisoning.
自2011年百草枯销售被禁止以来，韩国急性农药中毒相关死亡率显著下降。传统上，百草枯、敌草快以及几种高毒性有机磷、氨基甲酸酯和有机氯杀虫剂，一直被认为是导致急性农药中毒患者死亡的罪魁祸首。然而，尽管全球都在努力减少这些高毒性农药的使用，但某些农药的致死率仍超过其既定的临床毒性特征。了解这些农药的临床进展对医生和毒理学家至关重要，因为这有可能改善急性中毒病例中患者的预后。本综述旨在探讨此类高致死性农药的持续存在问题，它们继续对急性中毒受害者构成严重威胁。
