β-内啡肽2-9对下丘脑和边缘脑区中精氨酸加压素8和催产素水平的影响。
Effects of beta-endorphin2-9 on arginine-8-vasopressin and oxytocin levels in hypothalamic and limbic brain regions.
作者信息
Laczi F, Vecsernyés M, Kovács G L, Szabó G, Janáky T, Telegdy G, Lásló F A
出版信息
Brain Res. 1987 Feb 10;403(1):155-7. doi: 10.1016/0006-8993(87)90136-3.
PMID:3828809
Abstract
Immunoreactive arginine-8-vasopressin (AVP) and oxytocin (OXT) were measured in rat hypothalamic and limbic brain regions after the intracerebroventricular administration of beta-endorphin fragment 2-9 (beta E2-9). The peptide decreased the AVP content of the hippocampus and the OXT levels in the septum and amygdala. The present data favor the view that beta E2-9 interacts with limbic AVP- and OXT-systems.
摘要
在大鼠脑室内注射β-内啡肽片段2-9（βE2-9）后，检测了大鼠下丘脑和边缘脑区的免疫反应性精氨酸加压素（AVP）和催产素（OXT）。该肽降低了海马中的AVP含量以及隔区和杏仁核中的OXT水平。目前的数据支持βE2-9与边缘系统的AVP和OXT系统相互作用的观点。
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