The Roslin Institute & R(D)SVS, University of Edinburgh, Edinburgh, U.K.
Biochem Soc Trans. 2024 Feb 28;52(1):75-88. doi: 10.1042/BST20230197.
During embryonic development many organs and structures require the formation of series of repeating elements known as periodic patterns. Ranging from the digits of the limb to the feathers of the avian skin, the correct formation of these embryonic patterns is essential for the future form and function of these tissues. However, the mechanisms that produce these patterns are not fully understood due to the existence of several modes of pattern generation which often differ between organs and species. Here, we review the current state of the field and provide a perspective on future approaches to studying this fundamental process of embryonic development.
在胚胎发育过程中,许多器官和结构需要形成一系列称为周期性模式的重复元素。从肢体的趾到鸟类皮肤的羽毛,这些胚胎模式的正确形成对于这些组织的未来形态和功能至关重要。然而,由于存在几种模式生成方式,这些模式的产生机制尚未完全理解,而且这些方式通常在器官和物种之间存在差异。在这里,我们回顾了该领域的现状,并提供了一种研究胚胎发育这一基本过程的未来方法的视角。