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心脏电生理学中的经济分析:从临床疗效到成本效用。

Economic analyses in cardiac electrophysiology: from clinical efficacy to cost utility.

机构信息

Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Bvld 99, DK-8200 Aarhus, Denmark.

Department of Clinical Medicine, Aarhus University, Palle Juul-Jensens Bvld. 99, DK-8200 Aarhus, Denmark.

出版信息

Europace. 2024 Feb 1;26(2). doi: 10.1093/europace/euae031.

DOI:10.1093/europace/euae031
PMID:38289720
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10858642/
Abstract

Cardiac electrophysiology is an evolving field that relies heavily on costly device- and catheter-based technologies. An increasing number of patients with heart rhythm disorders are becoming eligible for cardiac interventions, not least due to the rising prevalence of atrial fibrillation and increased longevity in the population. Meanwhile, the expansive costs of healthcare face finite societal resources, and a cost-conscious approach to new technologies is critical. Cost-effectiveness analyses support rational decision-making in healthcare by evaluating the ratio of healthcare costs to health benefits for competing therapies. They may, however, be subject to significant uncertainty and bias. This paper aims to introduce the basic concepts, framework, and limitations of cost-effectiveness analyses to clinicians including recent examples from clinical electrophysiology and device therapy.

摘要

心脏电生理学是一个不断发展的领域,严重依赖昂贵的设备和基于导管的技术。越来越多的心律紊乱患者有资格接受心脏介入治疗,这主要是由于房颤的发病率上升和人口寿命延长。与此同时,医疗保健的高昂成本面临着有限的社会资源,因此对新技术采取具有成本意识的方法至关重要。成本效益分析通过评估竞争疗法的医疗成本与健康效益的比率,为医疗保健中的合理决策提供支持。然而,它们可能会受到重大不确定性和偏差的影响。本文旨在向临床医生介绍成本效益分析的基本概念、框架和局限性,包括来自临床电生理学和器械治疗的最新实例。

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本文引用的文献

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2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2023 ACC/AHA/ACCP/HRS 指南:心房颤动的诊断与管理——美国心脏病学会/美国心脏协会联合临床实践指南委员会的报告。
Circulation. 2024 Jan 2;149(1):e1-e156. doi: 10.1161/CIR.0000000000001193. Epub 2023 Nov 30.
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Economic burden of cardiovascular diseases in the European Union: a population-based cost study.欧盟心血管疾病的经济负担:一项基于人群的成本研究。
Eur Heart J. 2023 Dec 1;44(45):4752-4767. doi: 10.1093/eurheartj/ehad583.
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Cardiac implantable electronic device implantation and device-related infection.
心脏植入式电子设备植入与设备相关感染。
Europace. 2023 Aug 2;25(9). doi: 10.1093/europace/euad208.
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Cost-effectiveness of an antibacterial envelope for infection prevention in patients undergoing cardiac resynchronization therapy reoperations in Denmark.丹麦接受心脏再同步治疗手术患者中使用抗菌信封预防感染的成本效益分析。
Europace. 2023 Jun 2;25(6). doi: 10.1093/europace/euad159.
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Cost-effectiveness of early rhythm control vs. usual care in atrial fibrillation care: an analysis based on data from the EAST-AFNET 4 trial.房颤管理中早期节律控制与常规治疗的成本效益比较:基于 EAST-AFNET 4 试验数据的分析。
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Circ Arrhythm Electrophysiol. 2023 May;16(5):e011585. doi: 10.1161/CIRCEP.122.011585. Epub 2023 Mar 21.
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