Balakrishnan A, Yang J, Beattie C W, Das Gupta T K, Nandi S
Cancer Lett. 1987 Mar;34(3):233-42. doi: 10.1016/0304-3835(87)90172-8.
Estrogen binding was measured by a whole cell receptor assay in epithelial cells isolated from 20 premenopausal patients with breast fibroadenomas. A high affinity specific binding for estrogens was detected in the epithelial cells isolated from all 20 fibroadenomas. A relationship between estrogen binding and the phase in the menstrual cycle of the patient has been observed. Cell culture experiments using serum-free medium have also shown that estrogen binding can be augmented by cortisol.
通过全细胞受体测定法，对从20名患有乳腺纤维腺瘤的绝经前患者分离出的上皮细胞中的雌激素结合情况进行了测量。在从所有20个纤维腺瘤中分离出的上皮细胞中，均检测到了对雌激素的高亲和力特异性结合。已观察到雌激素结合与患者月经周期阶段之间的关系。使用无血清培养基进行的细胞培养实验还表明，皮质醇可增强雌激素结合。
