Department of Forensic Medicine and Toxicology, Kathmandu University School of Medical Sciences, Dhulikhel, Kavrepalanchowk, Nepal.
Kathmandu University School of Medical Sciences, Dhulikhel, Kavrepalanchowk, Nepal.
JNMA J Nepal Med Assoc. 2023 Aug 1;61(264):639-642. doi: 10.31729/jnma.8142.
Poisoning is a serious public health issue in developing countries like Nepal. Information about poisoning may be helpful for poisoning prevention and hospital treatment, aiding in the development of measures that lower the morbidity and mortality associated with poisoning. This study aimed to find out the prevalence of poisoning among autopsies conducted in the Department of Forensic Medicine and Toxicology in a tertiary care centre.
A descriptive cross-sectional study was conducted among autopsied cases in the Department of Forensic Medicine and Toxicology in a tertiary care centre. Data from 1 October 2020 to 1 April 2022 was collected between 22 December 2022 to 30 December 2022 from records after receiving ethical approval from the Institutional Review Committee. All autopsied cases during the study period were included with the exclusion of decomposed bodies. Convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.
Among 399 autopsies, 63 (15.79%) (12.21-19.37, 95% Confidence Interval) were found to be cases of poisoning. Among 63 cases, 35 (55.56%) were male and 28 (44.44%) were female. The most common substance causing poisoning was unknown with 31 (49.21%) cases, followed by organophosphates with 24 (38.10%) cases and rodenticide with 8 (12.70%) cases.
The prevalence of poisoning among autopsies was found to be higher than similar studies conducted in similar settings.
autopsy; organophosphate poisoning; poisoning; suicide.
在尼泊尔等发展中国家，中毒是一个严重的公共卫生问题。有关中毒的信息可能有助于中毒预防和医院治疗，有助于制定降低与中毒相关发病率和死亡率的措施。本研究旨在了解在一家三级保健中心法医毒理学系进行的尸检中毒发生率。
在一家三级保健中心法医毒理学系进行描述性横断面研究。2022 年 12 月 22 日至 30 日，在获得机构审查委员会伦理批准后，从记录中收集了 2020 年 10 月 1 日至 2022 年 4 月 1 日期间的尸检案例数据。所有在研究期间进行的尸检案例均包括在内，不包括腐烂的尸体。使用便利抽样法。点估计值在 95%置信区间内计算。
在 399 例尸检中，发现 63 例（15.79%）（12.21-19.37，95%置信区间）为中毒病例。在 63 例中毒病例中，男性 35 例（55.56%），女性 28 例（44.44%）。导致中毒的最常见物质是未知物质，有 31 例（49.21%），其次是有机磷，有 24 例（38.10%），杀鼠剂有 8 例（12.70%）。
尸检中毒发生率高于在类似环境中进行的类似研究。
尸检；有机磷中毒；中毒；自杀。
