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成人血液恶性肿瘤患者对 COVID-19 疫苗接种的态度。

Attitudes towards COVID-19 Vaccination in Adults with Haematological Malignancies.

机构信息

Central Coast Haematology, North Gosford, New South Wales, Australia.

School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.

出版信息

Acta Haematol. 2024;147(5):543-554. doi: 10.1159/000536548. Epub 2024 Feb 16.

DOI:10.1159/000536548
PMID:38290477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11441379/
Abstract

INTRODUCTION

Despite people with haematological malignancies being particularly vulnerable to severe COVID-19 infection and complications, vaccine hesitancy may be a barrier to optimal vaccination. This study explored attitudes towards COVID-19 vaccination in people with haematological malignancies.

METHODS

People with haematological malignancies at nine Australian health services were surveyed between June and October 2021. Sociodemographic and clinical characteristics were collected. Attitudes towards COVID-19 vaccination were explored using the Oxford COVID-19 Vaccine Hesitancy Scale, the Oxford COVID-19 Vaccine Confidence and Complacency Scale, and the Disease Influenced Vaccine Acceptance Scale-Six. Open-ended comments were qualitatively analysed.

RESULTS

A total of 869 people with haematological malignancies (mean age 64.2 years, 43.6% female) participated. Most participants (85.3%) reported that they had received at least one COVID-19 vaccine dose. Participants who were younger, spoke English as a non-dominant language, and had a shorter time since diagnosis were less likely to be vaccinated. Those who were female or spoke English as their non-dominant language reported greater vaccine side-effect concerns. Younger participants reported greater concerns about the vaccine impacting their treatment.

CONCLUSION

People with haematological malignancies reported high vaccine uptake; however, targeted education for specific participant groups may address vaccine hesitancy concerns, given the need for COVID-19 vaccine boosters.

摘要

简介

尽管血液系统恶性肿瘤患者特别容易受到严重 COVID-19 感染和并发症的影响,但疫苗犹豫可能是实现最佳接种的障碍。本研究探讨了血液系统恶性肿瘤患者对 COVID-19 疫苗接种的态度。

方法

2021 年 6 月至 10 月,在澳大利亚 9 家医疗服务机构对血液系统恶性肿瘤患者进行了调查。收集了社会人口统计学和临床特征。使用牛津 COVID-19 疫苗犹豫量表、牛津 COVID-19 疫苗信心和自满量表以及疾病影响疫苗接受度量表-六度来探讨对 COVID-19 疫苗接种的态度。对开放式评论进行了定性分析。

结果

共有 869 名血液系统恶性肿瘤患者(平均年龄 64.2 岁,43.6%为女性)参与了研究。大多数参与者(85.3%)报告至少接种了一剂 COVID-19 疫苗。年龄较小、英语非母语且诊断后时间较短的参与者接种疫苗的可能性较小。女性或英语非母语的参与者报告了更多的疫苗副作用担忧。年轻参与者对疫苗影响治疗的担忧更大。

结论

血液系统恶性肿瘤患者报告了高疫苗接种率;然而,鉴于需要 COVID-19 疫苗加强针,针对特定患者群体的有针对性的教育可能会解决疫苗犹豫问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37c7/11441379/d34d6eacc792/aha-2024-0147-0005-536548_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37c7/11441379/d96f6428cedf/aha-2024-0147-0005-536548_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37c7/11441379/d34d6eacc792/aha-2024-0147-0005-536548_F02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37c7/11441379/d96f6428cedf/aha-2024-0147-0005-536548_F01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/37c7/11441379/d34d6eacc792/aha-2024-0147-0005-536548_F02.jpg

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