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乳糜泻影响全球人口的 1%:谁来管理所有这些患者?

Celiac Disease Affects 1% of Global Population: Who Will Manage All These Patients?

机构信息

Celiac Disease Research Center, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland; Tampere Center for Child, Adolescent, and Maternal Health Research, Tampere University, Tampere, Finland; Department of Pediatrics, Tampere University Hospital, Tampere, Finland; University Consortium of Seinäjoki, Seinäjoki, Finland.

Department of Gastroenterology, Amsterdam University Medical Center, Amsterdam, The Netherlands; Location Vrije Universiteit, Amsterdam, The Netherlands.

出版信息

Gastroenterology. 2024 Jun;167(1):148-158. doi: 10.1053/j.gastro.2023.12.026. Epub 2024 Jan 28.

DOI:10.1053/j.gastro.2023.12.026
PMID:38290622
Abstract

Celiac disease is a common gastrointestinal condition with an estimated global prevalence of up to 1%. Adequate long-term surveillance of patients is imperative to ensure strict adherence to treatment with a gluten-free diet and the ensuing clinical and histologic recovery. Traditionally, this has been accomplished by means of regular on-site attendance at specialist health care facilities, accompanied for most patients by follow-up endoscopic and laboratory tests. However, the rapidly increasing prevalence of celiac disease and the limited health care resources challenge the current centralized and nonindividualized follow-up strategies. The improved noninvasive surveillance tools and online health care services are further changing the landscape of celiac disease management. There is a clear need for more personalized and on-demand follow-up based on early treatment response and patient-related factors associated with long-term prognosis. Additional scientific evidence on the optimal implementation of follow-up for pediatric and adulthood celiac disease is nevertheless called for.

摘要

乳糜泻是一种常见的胃肠道疾病,全球估计患病率高达 1%。为了确保严格遵循无麸质饮食治疗,并随之实现临床和组织学恢复,对患者进行充分的长期监测至关重要。传统上,这是通过定期在专门的医疗保健机构现场就诊来实现的,大多数患者还需要进行内镜和实验室检查。然而,乳糜泻的患病率迅速上升和有限的医疗保健资源对当前的集中式和非个体化的随访策略提出了挑战。改进的非侵入性监测工具和在线医疗保健服务正在进一步改变乳糜泻管理的格局。显然需要根据早期治疗反应和与长期预后相关的患者因素,制定更个性化和按需的随访策略。然而,仍需要更多关于儿科和成人乳糜泻随访最佳实施的科学证据。

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