Tobeigei Faisal Hassan, Joseph Martin R, Al-Hakami Ahmed, Hamid Mohamed E
Dermatology Division, Department of Internal Medicine, College of Medicine, King Khalid University, Abha, SAU.
Department of Clinical Microbiology and Parasitology, King Khalid University, Abha, SAU.
Cureus. 2023 Dec 31;15(12):e51402. doi: 10.7759/cureus.51402. eCollection 2023 Dec.
Background and purpose The complex is a globally distributed group of geophilic dermatophytes that primarily affect animals but can also rarely cause dermatomycoses in humans. With some regional and occupational variations, tinea corporis is the most prevalent presentation of the infection. The aim of this study was to report on the diagnosis and treatment of dermatophytosis cases among related families, and their pets, from southern Saudi Arabia. Up-to-date information on dermatophytes and dermatophytosis is needed. Methods This is a prospective case series undertaken at the Dermatology Outpatient Clinic of King Khalid University, Saudi Arabia. Six patients with suspected dermatophytosis were received at our hospital in 2022 and have been followed for recovery with or without scars. Characteristics of fungal pathogens were examined phenotypically on the basis of microscopic and growth characteristics, and laboratory data were used to initiate treatment with oral fluconazole, topical terbinafine cream, or oral itraconazole. Results Clinical features and culture results confirmed tinea capitis and tinea corporis caused by , which was also present in a pet cat. Tinea capitis cases (n = 4) did not respond to fluconazole and terbinafine treatment, but treatment with itraconazole resulted in a full recovery. Tinea corporis cases (n = 2) were treated with terbinafine, which resulted in a full recovery within four weeks, with no signs of scarring. Conclusions presents with serious persistent lesions and is extremely contagious. Treatment is durable but challenging, and breaking the transmission chain is more difficult.
背景与目的 该复合体是一组全球分布的嗜土性皮肤癣菌，主要感染动物，但也很少能引起人类皮肤癣菌病。随着一些地区和职业差异，体癣是该感染最常见的表现形式。本研究的目的是报告沙特阿拉伯南部相关家庭及其宠物中皮肤癣菌病病例的诊断和治疗情况。需要有关皮肤癣菌和皮肤癣菌病的最新信息。方法 这是在沙特阿拉伯哈利德国王大学皮肤科门诊进行的一项前瞻性病例系列研究。2022年，我院接收了6例疑似皮肤癣菌病的患者，并对其康复情况进行了随访，观察有无疤痕。根据显微镜检查和生长特征对真菌病原体的特征进行表型检查，并利用实验室数据开始使用口服氟康唑、外用特比萘芬乳膏或口服伊曲康唑进行治疗。结果 临床特征和培养结果证实头癣和体癣由 引起，该菌也存在于一只宠物猫身上。4例头癣病例对氟康唑和特比萘芬治疗无反应，但伊曲康唑治疗使其完全康复。2例体癣病例用特比萘芬治疗，四周内完全康复，无疤痕迹象。结论 表现为严重的持续性病变，具有极强的传染性。治疗持久但具有挑战性，且打破传播链更为困难。
