Recent advances in steroidal glycoalkaloid biosynthesis in the genus .

Steroidal glycoalkaloids (SGAs) are specialized metabolites found in members of species, and are also known as toxic substances in food crops such as tomato (), potato (), and eggplant (). SGA biosynthesis can be divided into two main parts: formation of steroidal aglycones, which are derived from cholesterol, and glycosylation at the C-3 hydroxy group. This review focuses on recent studies that shed light on the complete process of the aglycone formation in SGA biosynthesis and structural diversification of SGAs by duplicated dioxygenases, as well as the development of non-toxic potatoes through genome editing using these findings.