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老年无移位股骨颈骨折采用髋螺钉或髋关节置换术后的无再次手术生存率。

Reoperation-free survival after hip screws or hip arthroplasty for undisplaced femoral neck fractures in the elderly.

作者信息

Wolf Olof, Ghukasyan Lakic Tatevik, Ljungdahl Johan, Sundkvist Jonas, Möller Michael, Rogmark Cecilia, Mukka Sebastian, Hailer Nils P

机构信息

Department of Surgical Sciences, Orthopaedics, Uppsala University, Uppsala, Sweden.

Uppsala Clinical Research Center, Uppsala, Sweden.

出版信息

Bone Jt Open. 2024 Feb 2;5(2):87-93. doi: 10.1302/2633-1462.52.BJO-2023-0143.R1.

Abstract

AIMS

Our primary aim was to assess reoperation-free survival at one year after the index injury in patients aged ≥ 75 years treated with internal fixation (IF) or arthroplasty for undisplaced femoral neck fractures (uFNFs). Secondary outcomes were reoperations and mortality analyzed separately.

METHODS

We retrieved data on all patients aged ≥ 75 years with an uFNF registered in the Swedish Fracture Register from 2011 to 2018. The database was linked to the Swedish Arthroplasty Register and the National Patient Register to obtain information on comorbidity, mortality, and reoperations. Our primary outcome, reoperation, or death at one year was analyzed using restricted mean survival time, which gives the mean time to either event for each group separately.

RESULTS

Overall, 3,909 patients presenting with uFNFs were included. Of these patients, 3,604 were treated with IF and 305 with primary arthroplasty. There were no relevant differences in age, sex, or comorbidities between groups. In the IF group 58% received cannulated screws and 39% hook pins. In the arthroplasty group 81% were treated with hemiarthroplasty and 19% with total hip arthroplasty. At one year, 32% were dead or had been reoperated in both groups. The reoperation-free survival time over one year of follow-up was 288 days (95% confidence interval (CI) 284 to 292) in the IF group and 279 days (95% CI 264 to 295) in the arthroplasty group, with p = 0.305 for the difference. Mortality was 26% in the IF group and 31% in the arthroplasty group at one year. Reoperation rates were 7.1% in the IF group and 2.3% in the arthroplasty group.

CONCLUSION

In older patients with a uFNF, reoperation-free survival at one year seems similar, regardless of whether IF or arthroplasty is the primary surgery. However, this comparison depends on the choice of follow-up time in that reoperations were more common after IF. In contrast, we found more early deaths after arthroplasty. Our study calls for a randomized trial comparing these two methods.

摘要

目的

我们的主要目的是评估年龄≥75岁的无移位股骨颈骨折(uFNFs)患者接受内固定(IF)或关节置换术后1年的无再次手术生存率。次要结局是分别分析再次手术情况和死亡率。

方法

我们检索了瑞典骨折登记处2011年至2018年登记的所有年龄≥75岁的uFNFs患者的数据。该数据库与瑞典关节置换登记处和国家患者登记处相链接,以获取有关合并症、死亡率和再次手术的信息。我们使用受限平均生存时间分析主要结局,即1年时的再次手术或死亡情况,该方法分别给出每组发生任一事件的平均时间。

结果

总体而言,纳入了3909例出现uFNFs的患者。其中,3604例接受IF治疗,305例接受初次关节置换术。两组在年龄、性别或合并症方面无相关差异。在IF组中,58%接受空心螺钉治疗,39%接受钩钉治疗。在关节置换组中,81%接受半髋关节置换术治疗,19%接受全髋关节置换术治疗。1年时,两组中32%的患者死亡或接受了再次手术。IF组随访1年以上的无再次手术生存时间为288天(95%置信区间(CI)284至292),关节置换组为279天(95%CI 264至295),差异p = 0.305。1年时,IF组死亡率为26%,关节置换组为31%。IF组再次手术率为7.1%,关节置换组为2.3%。

结论

在患有uFNFs的老年患者中,无论初次手术是IF还是关节置换术,1年时的无再次手术生存率似乎相似。然而,这种比较取决于随访时间的选择,因为IF后再次手术更常见。相比之下,我们发现关节置换术后早期死亡更多。我们的研究呼吁进行一项比较这两种方法的随机试验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e31d/10834084/fdceeace74a6/BJO-2023-0143.R1-galleyfig1.jpg

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