Cui Hongyi, Zhang Chunyan, Ji Yuqi, Zhang Guoying
State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Sciences Taiyuan 030001 P. R. China
University of Chinese Academy of Sciences Beijing 100049 China.
RSC Adv. 2024 Jan 31;14(7):4339-4344. doi: 10.1039/d4ra00189c.
A green and sustainable metal-free, additive-free olefination approach is proposed for the facile synthesis of various unsaturated -heteroazaarenes from simple methyl-substituted heteroarenes and amines. The developed protocol employs only air as the sole oxidant and provides a useful strategy for obtaining various -selective conjugated heterocyclic olefins. This provides a useful strategy for application in generating grams of a variety of unsaturated -heteroazaarenes (up to 20.33 grams) and the synthetic imaging agents of STB-8 (2.40 gram) with high regioselectivity in one pot.
提出了一种绿色可持续的无金属、无添加剂的烯化方法，用于从简单的甲基取代杂芳烃和胺轻松合成各种不饱和杂氮芳烃。所开发的方案仅使用空气作为唯一的氧化剂，并为获得各种区域选择性共轭杂环烯烃提供了一种有用的策略。这为一锅法制备克级的各种不饱和杂氮芳烃（高达20.33克）和具有高区域选择性的STB-8合成成像剂（2.40克）提供了一种有用的策略。
