Aljuhani Reyof, Adas Merna, Alnaami Raghad, Alshehri Reham, Alqarni Rahaf, NoorSaeed Sundus, Al-Agha Abdulmoein
Medicine, King Abdulaziz University Hospital, Jeddah, SAU.
Pediatrics, King Abdulaziz University, Jeddah, SAU.
Cureus. 2024 Jan 1;16(1):e51496. doi: 10.7759/cureus.51496. eCollection 2024 Jan.
Objectives We aimed to determine the benefits and drawbacks of real-time continuous glucose monitoring (rtCGM) compared with those of self-monitoring of blood glucose (SMBG) in children and adolescents with type 1 diabetes (T1D) and their impact on glycemic control, hypo- and hyperglycemic episodes, exercise, quality of life, and psychosocial factors. Methodology This quantitative, comparative, cross-sectional study was conducted between July 2022 and March 2023 at the Pediatric Endocrine Outpatient Clinic, King Abdulaziz University Hospital, Saudi Arabia. Data were obtained via a clinical interview with children and adolescents with T1D aged 2-18 years. Results The study involved 121 participants, with 71 (58.7%) male patients and 50 (41.3%) female patients. The participants' mean age was 11.9 ± 4.4 years. Compared with patients using SMBG, patients using rtCGM demonstrated a more significant decrease in the mean glycated hemoglobin (HbA1c) level from baseline (7.79 ± 1.17 vs. 8.92 ± 1.63, = 0.001), a reduction in the number of hypoglycemic episodes (85.7% vs. 70.6%, = 0.028), and stable blood glucose level during exercise (97.2% vs. 76.4%, = 0.001). Additionally, 65 (92.9%) rtCGM users had undisturbed sleep compared with 22 (43.1%) SMBG users. Approximately 64 (91.4%) rtCGM users reported that the sensor helped decrease their anxiety levels and pain sensations. Conclusions In this novel study in Saudi Arabia, rtCGM demonstrated a significantly better impact than SMBG on glycemic control, hypo- and hyperglycemic episodes, and psychosocial factors in children and adolescents with T1D.
目的 我们旨在确定与自我血糖监测（SMBG）相比，实时连续血糖监测（rtCGM）在1型糖尿病（T1D）儿童和青少年中的益处和缺点，以及其对血糖控制、低血糖和高血糖发作、运动、生活质量和心理社会因素的影响。方法 这项定量、比较性横断面研究于2022年7月至2023年3月在沙特阿拉伯阿卜杜勒阿齐兹国王大学医院儿科内分泌门诊进行。数据通过对2至18岁T1D儿童和青少年的临床访谈获得。结果 该研究涉及121名参与者，其中男性患者71名（58.7%），女性患者50名（41.3%）。参与者的平均年龄为11.9±4.4岁。与使用SMBG的患者相比，使用rtCGM的患者糖化血红蛋白（HbA1c）平均水平从基线开始有更显著下降（7.79±1.17 vs. 8.92±1.63，P = 0.001），低血糖发作次数减少（85.7% vs. 70.6%，P = 0.028），运动期间血糖水平稳定（97.2% vs. 76.4%，P = 0.001）。此外，65名（92.9%）rtCGM使用者睡眠不受干扰，而SMBG使用者为22名（43.1%）。约64名（91.4%）rtCGM使用者报告该传感器有助于降低他们的焦虑水平和疼痛感。结论 在沙特阿拉伯的这项新研究中，rtCGM在血糖控制、低血糖和高血糖发作以及心理社会因素方面对T1D儿童和青少年的影响明显优于SMBG。
