Behavioral Research in Technology and Engineering Center, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Behavioral Research in Technology and Engineering Center, Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, United States.
Psychiatry Res. 2024 Mar;333:115751. doi: 10.1016/j.psychres.2024.115751. Epub 2024 Jan 22.
Previous cross-sectional and laboratory research has identified risk factors for persecutory ideation including rumination, negative affect, and safety-seeking behaviors. Questions remain about what in-the-moment factors link general negative affect to PI as well as which maintain PI over time. In the present study, N = 219 individuals completed momentary assessments of PI as well as four factors (attributing threats as certain and important, ruminating, and changing one's behavior in response) proposed to maintain PI over time. Linear mixed effects models were used to analyze multiple time-varying relationships, including these factors predicting negative affect and vice versa, as well as factors predicting maintenance of PI over time. Linear mixed effects models were used to analyze multiple time-varying relationships, examining each PI-related factor predicting negative affect, negative affect predicting each PI-related factor, as well as each factor predicting maintenance of PI over time. All four factors were associated with increases in subsequent day self-reported severity of PI, suggesting all four increased the likelihood of maintaining or worsening next-day PI. Results of this study confirm that the proposed factors are key in maintaining a cycle by which PI and negative affect are maintained over time. These factors may represent targets for momentary interventions.
先前的横断面和实验室研究已经确定了偏执观念的风险因素,包括反刍思维、负性情绪和寻求安全的行为。目前仍不清楚是什么即时因素将一般负性情绪与 PI 联系起来,以及哪些因素能随时间维持 PI。在本研究中,有 219 名个体完成了 PI 的即时评估以及四个被认为可以随时间维持 PI 的因素(将威胁归因于确定和重要、反刍、以及根据威胁改变行为)。线性混合效应模型用于分析多个时变关系,包括这些因素预测负性情绪以及负性情绪预测这些因素,以及预测 PI 随时间维持的因素。线性混合效应模型用于分析多个时变关系,检验每个与 PI 相关的因素预测负性情绪、负性情绪预测每个与 PI 相关的因素,以及每个因素预测 PI 随时间维持的情况。所有四个因素都与随后一天自我报告的 PI 严重程度增加有关,这表明这四个因素都增加了维持或加重下一天 PI 的可能性。这项研究的结果证实,所提出的因素是维持 PI 和负性情绪随时间维持的循环的关键。这些因素可能是即时干预的目标。