De Luca F, Muritano M, Rizzo G, Pandullo E, Cardia E
Helv Paediatr Acta. 1985;40(6):467-72.
In 4/37 (10.8%) children, adolescents and young adults with successfully shunted hydrocephalus, puberty occurred or was occurring precociously, at an age ranging from 7.5 to 8.6 years, with a consequent impairment of their effective or predicted adult height as compared to the familial target height. All four patients had undergone a surgical intervention for the insertion of a ventricular-atrial or a ventricular-peritoneal shunt during the first year of life; since the last surgical shunt revision (at the age of 5 years) no relapse of hydrocephalus had been recorded. The authors conclude that precocious puberty is to be regarded as a not infrequent long-term complication in patients with successfully shunted hydrocephalus.
在37例脑积水成功分流的儿童、青少年和年轻成人中，有4例（10.8%）在7.5至8.6岁时出现或正在出现性早熟，与家族目标身高相比，其有效或预测的成人身高受到影响。所有4例患者在出生后第一年内均接受了脑室-心房或脑室-腹腔分流术；自上次手术分流术翻修（5岁时）以来，未记录到脑积水复发。作者得出结论，性早熟应被视为脑积水成功分流患者中一种较为常见的长期并发症。
