Graduate Program in Human Movement Sciences, Federal University of Pará, Belém, Pará, Brazil.
Graduate Program in Human Movement Sciences, Federal University of Pará, Belém, Pará, Brazil.
Exp Gerontol. 2024 Mar;187:112370. doi: 10.1016/j.exger.2024.112370. Epub 2024 Feb 6.
Frailty is associated with an increased susceptibility to functional decline, impairment, hospitalization, and mortality among the older adults. However, the potential reversibility of frailty lies in identifying modifiable factors that could prevent, mitigate, or interrupt its progression. While there is a suggestion that sleep disorders may increase the risk of frailty and impairment, the risk stratification of this relationship remains inconclusive.
Stratify the risk of frailty and impairment and investigate potential connections with sleep quality, excessive daytime sleepiness, and the risk of obstructive sleep apnea in older adults dwelling in the community.
This was a quantitative cross-sectional investigation. Frailty risk and impairment were stratified using the Frail Non-disabled Questionnaire (for impairment) and the FRAIL Scale (for Frailty). The assessment of excessive daytime sleepiness, sleep quality, and the risk of obstructive sleep apnea involved the employment of the Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, and the STOP-BANG questionnaire, respectively.
A total of 109 older adults living in the urban area (86 %, p = 0.010), females (61 %; p = 0.030), median age 68 (64-75) years, with overweight (36 %, p < 0.010) and self-identified as belonging to other racial or ethnic categories (71 %, p < 0.010). According to the impairment assessment, 32 % of participants were classified as disable (p < 0.01). Conversely, as per the frailty evaluation, 33 % were pre-frail and 25 % were identified as frail. Additionally, a substantial proportion experienced poor sleep quality (80 %, p = 0.010), exhibited a moderate risk of obstructive sleep apnea (49 %, p < 0.010), and showed no signs of excessive daytime sleepiness (62 %, p < 0.010). There was a modest correlation between frailty and impairment with poor sleep quality (rho = 0.39; p < 0.001) and the risk of obstructive sleep apnea (rho = 0.26; p = 0.000). However, the was no significant relationship was observed between frailty and impairment and excessive daytime sleepiness (rho = 0.04; p = 0.660). Similarly, a modest correlation was observed between sleep quality (rho = 0.33; p < 0.001), the risk of obstructive sleep apnea (rho = 0.27; p = 0.001), and frailty. Conversely, no correlation was found with excessive daytime sleepiness (rho = 0.05; p = 0.590). Also, the poor sleep quality and the risk of obstructive sleep apnea explain 14 % of the risk of frailty in the population of community-dwelling older adults (r = 0.14; p = 0.04).
This study reveals a modest risk of frailty and impairment with sleep quality and the risk of obstructive sleep apnea, but not with excessive daytime sleepiness in community-dwelling older adults.
虚弱与老年人功能下降、损伤、住院和死亡的易感性增加有关。然而，虚弱的潜在可逆转性在于确定可改变的因素，这些因素可以预防、减轻或中断其进展。虽然有研究表明睡眠障碍可能会增加虚弱和损伤的风险，但这种关系的风险分层仍不确定。
对居住在社区的老年人的虚弱和损伤风险进行分层，并研究与睡眠质量、日间嗜睡过多和阻塞性睡眠呼吸暂停风险的潜在联系。
这是一项定量的横断面研究。使用虚弱非残疾问卷（用于损伤）和 FRAIL 量表（用于虚弱）对虚弱风险和损伤进行分层。使用 Epworth 嗜睡量表、匹兹堡睡眠质量指数和 STOP-BANG 问卷分别评估日间嗜睡过多、睡眠质量和阻塞性睡眠呼吸暂停的风险。
共有 109 名居住在城市地区的老年人（86%，p=0.010），女性（61%，p=0.030），中位年龄 68（64-75）岁，超重（36%，p<0.010）和自我认同属于其他种族或族裔类别的（71%，p<0.010）。根据损伤评估，32%的参与者被归类为残疾（p<0.01）。相反，根据虚弱评估，33%的参与者被认为是虚弱前期，25%的参与者被认为是虚弱。此外，相当一部分人睡眠质量较差（80%，p=0.010），患有中度阻塞性睡眠呼吸暂停风险（49%，p<0.010），且没有日间嗜睡过多的迹象（62%，p<0.010）。虚弱和损伤与睡眠质量差（rho=0.39；p<0.001）和阻塞性睡眠呼吸暂停风险（rho=0.26；p=0.000）之间存在中度相关性。然而，虚弱和损伤与日间嗜睡过多（rho=0.04；p=0.660）之间没有显著关系。同样，睡眠质量（rho=0.33；p<0.001）、阻塞性睡眠呼吸暂停风险（rho=0.27；p=0.001）和虚弱之间也存在中度相关性。相反，与日间嗜睡过多（rho=0.05；p=0.590）无相关性。此外，睡眠质量差和阻塞性睡眠呼吸暂停风险解释了社区居住的老年人虚弱风险的 14%（r=0.14；p=0.04）。
本研究表明，在社区居住的老年人中，虚弱和损伤与睡眠质量和阻塞性睡眠呼吸暂停风险存在中度风险，但与日间嗜睡过多无关。
