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眼周鳞状细胞癌的手术治疗:病例报告

Surgical management of periocular squamous cell carcinoma: case report.

作者信息

Alexa Anisia-Iuliana, Leferman Carmen-Ecaterina, Ciubotaru Alin Dumitru, Maștaleru Alexandra, Abdulan Irina Mihaela, Leon Maria Magdalena

机构信息

Department of Ophthalmology, "Grigore T. Popa" University of Medicine and Pharmacy, Iași, Romania.

Department of Pharmacology, "Grigore T. Popa" University of Medicine and Pharmacy, Iași, Romania.

出版信息

J Med Life. 2023 Oct;16(10):1571-1574. doi: 10.25122/jml-2023-0537.

Abstract

This report describes the case of a 72-year-old female patient admitted to the ophthalmology clinic for a large round-oval tumor with a long-standing keratotic lesion on her lower eyelid, without extending to the free margin of the eyelid. The tumor was excised with a margin in non-tumorous tissue, the nearest being 1 mm away from the tumor at the 12 o'clock position. The surgical process was complicated by the patient's treatment with the anticoagulant rivaroxaban, resulting in increased bleeding during surgery. The histopathological evaluation showed characteristics indicative of a well-differentiated squamous cell carcinoma, more specifically, the keratoacanthoma type. Consequently, it was necessary to extend the excision at the 12 o'clock position by an additional 3 mm. The procedure involved extensive removal of the impacted area and subsequent reconstruction with advancement flaps, supported by histological examination to ensure total excision. In cases of squamous cell carcinoma on the eyelid, multiple sequential excisions are often required to ensure complete removal within safe histological margins, achieving desirable functional and esthetic results.

摘要

本报告描述了一名72岁女性患者的病例,该患者因下眼睑出现一个大的圆形 - 椭圆形肿瘤且伴有长期角化病变而入住眼科诊所,肿瘤未延伸至眼睑游离缘。肿瘤在非肿瘤组织中带边缘切除,在12点位置距肿瘤最近处为1毫米。手术过程因患者正在接受抗凝药物利伐沙班治疗而变得复杂,导致手术期间出血增加。组织病理学评估显示出特征性表现,提示为高分化鳞状细胞癌,更具体地说是角化棘皮瘤型。因此,有必要在12点位置将切除范围再扩大3毫米。该手术包括广泛切除受影响区域,随后用推进皮瓣进行重建,并通过组织学检查来确保完全切除。对于眼睑鳞状细胞癌病例,通常需要多次连续切除,以确保在安全的组织学边缘内完全切除,从而获得理想的功能和美学效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/462c/10835559/6ee66463c27c/JMedLife-16-1571-g001.jpg

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