Garcia Jasmine, Bryson Staci, Mansueto Lisa A
From the Medical College of Wisconsin, Milwaukee, Wis.
Medical Director Pathology Department, Banner Desert Medical Center/Banner Children's at Desert, Mesa, Ariz.
Plast Reconstr Surg Glob Open. 2024 Feb 1;12(2):e5569. doi: 10.1097/GOX.0000000000005569. eCollection 2024 Feb.
Giant cell tumor of bone (GCTB) typically presents in the epiphysis of long bones and occurs in the skull in less than 1% of cases. When GCTB is diagnosed in the skull, it is primarily seen in the temporal and sphenoid bones. GCTB is an osteoclastic stromal tumor that is locally aggressive and tends to recur. We present a case of a 43-year-old woman with slowly progressive, left-sided proptosis, eyelid swelling, photophobia, epiphora, and pressure sensation. Computed tomography and magnetic resonance imaging revealed an enhancing tumor in the left inferior orbit with infiltration into the maxillary sinus roof. Histological examination was conclusive for a giant cell tumor of the maxillary bone presenting as an inferior orbital mass. Gross total surgical resection was performed via an inferior anterior orbitotomy, and the patient had resolution of symptoms without recurrence in her postoperative course to date. This report contributes to the scarce literature available on this type of tumor of skull bones, specifically presenting the first case in the maxillary bone of the floor of the orbit.
骨巨细胞瘤（GCTB）通常出现在长骨的骨骺部位，发生于颅骨的病例不到1%。当颅骨被诊断为GCTB时，主要见于颞骨和蝶骨。GCTB是一种破骨性基质肿瘤，具有局部侵袭性且易于复发。我们报告一例43岁女性病例，患者有缓慢进展的左侧眼球突出、眼睑肿胀、畏光、流泪及压迫感。计算机断层扫描和磁共振成像显示左眼眶下部有一强化肿瘤，并侵入上颌窦顶。组织学检查确诊为上颌骨巨细胞瘤，表现为眼眶下部肿块。通过眶下前路开眶术进行了肿瘤全切术，患者症状消失，术后至今未复发。本报告为关于这种颅骨肿瘤的稀少文献增添了内容，特别是报道了眼眶底部上颌骨的首例病例。
