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骨巨细胞瘤:从眶内肿物到骨内肿物的行为变化

Giant Cell Tumor: Changing Behavior from Intraorbital to Intraosseous Mass.

作者信息

Rajabi Mohammad Taher, Poursayed Lazarjani Seyedeh Zahra, Mohammadi S Saeed, Veshagh Mohammad, Hosseinzadeh Farideh, Rafizadeh Seyed Mohsen, Amoli Fahimeh Asadi, Hosseini Simindokht

机构信息

Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Eye Research Center, Labbafinejad Eye Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

J Curr Ophthalmol. 2020 Dec 12;32(4):414-416. doi: 10.4103/JOCO.JOCO_63_20. eCollection 2020 Oct-Dec.

DOI:10.4103/JOCO.JOCO_63_20
PMID:33553846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7861103/
Abstract

PURPOSE

To present a patient with giant cell tumor (GCT) of the orbit by changing behavior from an intraorbital mass to an intraosseous tumor.

METHODS

A 16-year-old boy presented with pain, swelling, erythematous of the left upper and lower eyelids, proptosis, and diplopia. Ophthalmic examination revealed chemosis, conjunctival injection, limited elevation, depression as well as abduction in the left eye.

RESULTS

Multislice computed tomography scan (CT scan) of the orbit and paranasal sinuses showed a hyperdense, oval, extraconal mass with bone erosion. Magnetic resonance imaging of the orbit showed an inferior lateral isointense, oval, extraconal mass that had indented the globe. The patient underwent superior lateral orbitotomy, and the orbital mass was excised. Two months later, the patient developed proptosis, severe chemosis, and eyelid erythema in the same eye. CT scan showed an intraosseous mass in the lateral wall of the orbit that had pushed the globe anteromedially. Intraosseous tumor was resected, and the lateral orbital wall was drilled during the second surgery. GCT was diagnosed based on pathological survey.

CONCLUSION

Following the resection of the orbital GCT, the tumor behavior may change to an intraosseous lesion.

摘要

目的

报告1例眼眶骨巨细胞瘤(GCT),其表现从眶内肿块转变为骨内肿瘤。

方法

一名16岁男孩出现左上、下眼睑疼痛、肿胀、红斑、眼球突出和复视。眼科检查发现左眼结膜水肿、结膜充血、上抬受限、下转受限以及外展受限。

结果

眼眶和鼻窦的多层计算机断层扫描(CT扫描)显示一个高密度椭圆形眶锥外肿块伴有骨质侵蚀。眼眶磁共振成像显示一个位于下外侧等信号的椭圆形眶锥外肿块,该肿块使眼球受压。患者接受了眶上外侧切开术,切除了眼眶肿块。两个月后,患者同一只眼睛再次出现眼球突出、严重结膜水肿和眼睑红斑。CT扫描显示眼眶外侧壁有一个骨内肿块,将眼球向前内侧推移。第二次手术切除了骨内肿瘤,并对眼眶外侧壁进行了钻孔。根据病理检查诊断为骨巨细胞瘤。

结论

眼眶骨巨细胞瘤切除后,肿瘤表现可能转变为骨内病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/c74d4f9fd547/JCO-32-414-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/fefe0de923eb/JCO-32-414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/151646c0a0b4/JCO-32-414-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/9848c292caec/JCO-32-414-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/c74d4f9fd547/JCO-32-414-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/fefe0de923eb/JCO-32-414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/151646c0a0b4/JCO-32-414-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/9848c292caec/JCO-32-414-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e2/7861103/c74d4f9fd547/JCO-32-414-g004.jpg

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本文引用的文献

1
Giant cell tumour of frontal bone in a patient with bilateral retinoblastoma.
Arch Soc Esp Oftalmol (Engl Ed). 2019 Apr;94(4):200-203. doi: 10.1016/j.oftal.2018.10.003. Epub 2018 Nov 16.
2
Denosumab in Patients with Giant Cell Tumor and Its Recurrence: A Systematic Review.地诺单抗治疗骨巨细胞瘤及其复发患者的系统评价
Arch Bone Jt Surg. 2018 Jul;6(4):260-268.
3
Left orbital roof giant cell tumor of bone: A case report.左眼眶顶骨巨细胞瘤:一例报告。
Surg Neurol Int. 2018 Jun 26;9:127. doi: 10.4103/sni.sni_467_17. eCollection 2018.
4
Giant Cell Tumor of the Lateral Skull Base: Diagnostic and Management Options.外侧颅底巨细胞瘤:诊断与治疗选择
J Neurol Surg Rep. 2018 Apr;79(2):e41-e54. doi: 10.1055/s-0038-1645885. Epub 2018 May 25.
5
Denosumab treatment for progressive skull base giant cell tumor of bone in a 14 year old female - a case report and literature review.地诺单抗治疗一名14岁女性进展性颅底骨巨细胞瘤——病例报告及文献综述
Ital J Pediatr. 2017 Mar 29;43(1):32. doi: 10.1186/s13052-017-0353-0.
6
Giant Cell Tumor of the Frontal Bone Presenting as an Orbital Mass.表现为眼眶肿物的额骨巨细胞瘤
Ophthalmol Ther. 2017 Jun;6(1):215-220. doi: 10.1007/s40123-017-0081-y. Epub 2017 Feb 16.
7
Treatment of a skull-base giant cell tumor with endoscopic endonasal resection and denosumab: case report.内镜经鼻颅底巨大细胞瘤切除术联合地舒单抗治疗:病例报告。
J Neurosurg. 2017 Feb;126(2):431-434. doi: 10.3171/2016.3.JNS152802. Epub 2016 May 13.
8
Giant Cell Tumor of Bone - An Overview.骨巨细胞瘤——概述
Arch Bone Jt Surg. 2016 Jan;4(1):2-9.
9
Giant Cell Tumor of the Skull: Review of the Literature.颅骨巨细胞瘤:文献综述
J Neurol Surg A Cent Eur Neurosurg. 2016 May;77(3):239-46. doi: 10.1055/s-0035-1554808. Epub 2015 Jun 19.
10
RANKL, denosumab, and giant cell tumor of bone.RANKL、地舒单抗和骨巨细胞瘤。
Curr Opin Oncol. 2012 Jul;24(4):397-403. doi: 10.1097/CCO.0b013e328354c129.