Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Abrahama 58, Gdansk 80-307, Poland.
Institute of Physics, School of Basic Sciences, École Polytechnique Fédérale de Lausanne - EPFL, Lausanne CH 1015, Switzerland; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne - EPFL, Lausanne CH 1015, Switzerland.
Cell Stress Chaperones. 2024 Feb;29(1):21-33. doi: 10.1016/j.cstres.2023.12.002. Epub 2023 Dec 23.
J-domain proteins (JDPs) are the largest family of chaperones in most organisms, but much of how they function within the network of other chaperones and protein quality control machineries is still an enigma. Here, we report on the latest findings related to JDP functions presented at a dedicated JDP workshop in Gdansk, Poland. The report does not include all (details) of what was shared and discussed at the meeting, because some of these original data have not yet been accepted for publication elsewhere or represented still preliminary observations at the time.
J 结构域蛋白(JDPs)是大多数生物体中最大的伴侣蛋白家族,但它们在其他伴侣蛋白和蛋白质质量控制机制网络中的功能仍有许多未解之谜。在这里,我们报告了在波兰格但斯克举行的专门的 JDP 研讨会上介绍的与 JDP 功能相关的最新发现。该报告并未包含会议上分享和讨论的所有(细节)内容,因为其中一些原始数据尚未在其他地方发表,或者当时仍代表初步观察结果。