Department of Dermatology, Mater Dei Hospital, Msida, Malta; Department of Pathology, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.
Department of Anatomy, Faculty of Medicine and Surgery, University of Malta, Msida, Malta; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.
Hum Immunol. 2024 Mar;85(2):110764. doi: 10.1016/j.humimm.2024.110764. Epub 2024 Feb 6.
Hidradenitis suppurativa is a chronic, inflammatory condition of the pilosebaceous unit in which patients manifest multiple, painful cutaneous nodules, abscesses and tunnels. These lesions are described to affect the intertriginous zones, however, the condition exhibits significant phenotypic variability. Such variability is influenced by the patients lifestyle, genetic predisposition and sex. In this cross-sectional study, we investigate sex differences in patterns of hidradenitis suppurativa skin involvement, specifically at site of first involvement and most bothersome cutaneous site of involvement.
化脓性汗腺炎是一种毛囊皮脂腺单位的慢性炎症性疾病,患者表现为多个疼痛性皮肤结节、脓肿和瘘管。这些病变被描述为影响皱褶部位,但该疾病表现出显著的表型变异性。这种变异性受患者生活方式、遗传易感性和性别影响。在这项横断面研究中,我们研究了化脓性汗腺炎皮肤受累模式中的性别差异,特别是首次受累部位和最困扰的皮肤受累部位。