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青少年心血管健康轨迹及其与西班牙社会人口统计学和心血管代谢结局的关系。

Cardiovascular Health Trajectories in Adolescence and Their Association With Sociodemographic and Cardiometabolic Outcomes in Spain.

机构信息

Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain.

Centro Nacional de Investigaciones Cardiovasculares (CNIC), Madrid, Spain; Foundation for Science, Health and Education (SHE), Barcelona, Spain.

出版信息

J Adolesc Health. 2024 May;74(5):1039-1048. doi: 10.1016/j.jadohealth.2023.12.016. Epub 2024 Feb 6.

Abstract

PURPOSE

To determine cardiovascular health (CVH) trajectories and their association with sociodemographic and cardiometabolic outcomes in adolescence.

METHODS

One thousand eighty adolescents attending 24 secondary schools enrolled in the SI! Program for Secondary Schools trial in Spain were assessed at approximately 12, 14, and 16 years of age. CVH was assessed according to American Heart Association criteria based on seven metrics (smoking status, body mass index, physical activity, diet, blood pressure, total cholesterol, and blood glucose), and CVH trajectories were identified by latent class trajectory modeling. Associations between CVH trajectories, sociodemographic characteristics, and cardiometabolic outcomes were analyzed using generalized linear and Poisson models.

RESULTS

Five CVH trajectory groups were identified: poor-stable (27 adolescents [2.5%]), intermediate-substantial rise (79 [7.3%]), intermediate-substantial decline (63 [5.8%]), intermediate-mild decline (403 [37.3%]), and intermediate-mild rise (508 [47.1%]). Boys and adolescents from families with low-average income, low-intermediate educational attainment, and a migrant background more frequently belonged to groups with lower baseline CVH and poor or declining trajectories. The intermediate-substantial decline group had the highest prevalence ratio for overweight/obesity (3.84; 95% confidence interval: 2.86-5.16) and metabolic syndrome (4.93; 95% confidence interval: 1.21-20.04) at age 16, whereas prevalence was lowest in the intermediate-mild rise group.

DISCUSSION

Adolescent CVH trajectories differ according to socioeconomic characteristics and are associated with cardiometabolic outcomes. Primordial prevention interventions should be implemented early in life, taking into account CVH trajectories and with a particular focus on vulnerable populations.

摘要

目的

确定青少年心血管健康 (CVH) 轨迹及其与社会人口统计学和心血管代谢结局的关系。

方法

在西班牙的 SI!中学计划试验中,共有 1080 名青少年在 24 所中学就读,他们在大约 12、14 和 16 岁时接受评估。根据美国心脏协会的标准,根据七个指标(吸烟状况、体重指数、身体活动、饮食、血压、总胆固醇和血糖)评估 CVH,并通过潜在类别轨迹建模确定 CVH 轨迹。使用广义线性和泊松模型分析 CVH 轨迹、社会人口统计学特征和心血管代谢结局之间的关联。

结果

确定了 5 种 CVH 轨迹组:差-稳定组(27 名青少年[2.5%])、中-显著上升组(79 名[7.3%])、中-显著下降组(63 名[5.8%])、中-轻度下降组(403 名[37.3%])和中-轻度上升组(508 名[47.1%])。男孩和来自低收入家庭、低-中等教育程度和移民背景的青少年更频繁地属于基线 CVH 较低且 CVH 较差或下降的组。中-显著下降组超重/肥胖的患病率比最高(3.84;95%置信区间:2.86-5.16)和代谢综合征(4.93;95%置信区间:1.21-20.04)在 16 岁时,而中-轻度上升组的患病率最低。

讨论

青少年 CVH 轨迹因社会经济特征而异,并与心血管代谢结局相关。应在生命早期实施初级预防干预措施,同时考虑 CVH 轨迹,并特别关注弱势群体。

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