Universidade Federal do Paraná, Hospital de Clínicas, Curitiba, PR, Brasil.
Universidade Federal do Paraná, Programa de Pós-Graduação em Microbiologia, Parasitologia e Patologia, Curitiba, PR, Brasil.
Rev Soc Bras Med Trop. 2024 Feb 5;57:e008002023. doi: 10.1590/0037-8682-0480-2024. eCollection 2024.
Previously considered saprobe and non-pathogenic, the fungus Papiliotrema laurentii (formerly known as Cryptococcus laurentii), is rarely associated with human infection. Nevertheless, there has been an increase in reported infections by non-neoformans cryptococci. After a literature search on the Cochrane Library, LILACS, SciELO, MEDLINE, PubMed, and PMC (PubMed Central) databases, we conclude that this is the first case report of fungemia and probable meningitis caused by Papiliotrema laurentii in a previously immunocompetent host with associated COVID-19.
先前被认为是腐生菌且无致病性的真菌,即蜡盘革耳菌(以前被称为Laurentii 隐球菌),很少与人类感染有关。然而,由非新型隐球菌引起的感染报告有所增加。在对 Cochrane 图书馆、LILACS、SciELO、MEDLINE、PubMed 和 PMC(PubMed 中心)数据库进行文献检索后,我们得出结论,这是首例先前免疫功能正常的 COVID-19 宿主感染蜡盘革耳菌引起菌血症和可能的脑膜炎的病例报告。