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Disseminated Cryptococcosis in a Patient With Metastatic Prostate Cancer Who Died in the Coronavirus Disease 2019 (COVID-19) Outbreak.一名转移性前列腺癌患者在2019年冠状病毒病（COVID-19）疫情期间死于播散性隐球菌病。
Cureus. 2020 May 23;12(5):e8254. doi: 10.7759/cureus.8254.
2
Effective treatment of severe COVID-19 patients with tocilizumab.托珠单抗治疗重症 COVID-19 患者有效。
Proc Natl Acad Sci U S A. 2020 May 19;117(20):10970-10975. doi: 10.1073/pnas.2005615117. Epub 2020 Apr 29.
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Decreasing incidence of cryptococcal meningitis in West Africa in the era of highly active antiretroviral therapy.高效抗逆转录病毒治疗时代西非隐球菌性脑膜炎发病率的下降。
AIDS. 2012 May 15;26(8):1039-41. doi: 10.1097/QAD.0b013e328352d1d8.
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Spores as infectious propagules of Cryptococcus neoformans.作为新型隐球菌感染性繁殖体的孢子。
Infect Immun. 2009 Oct;77(10):4345-55. doi: 10.1128/IAI.00542-09. Epub 2009 Jul 20.
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Tissue changes and tissue diagnosis in cryptococcosis; a study of 26 cases.隐球菌病的组织变化与组织诊断；26例研究
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Cryptococcaemia: clinical features and prognostic factors.隐球菌血症：临床特征及预后因素
QJM. 2002 Aug;95(8):511-8. doi: 10.1093/qjmed/95.8.511.
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Cryptococcus neoformans var. grubii: separate varietal status for Cryptococcus neoformans serotype A isolates.新型隐球菌格鲁比变种：新型隐球菌A血清型分离株的独立变种地位。
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Pathology of cryptococcal meningoencephalitis: analysis of 27 patients with pathogenetic implications.隐球菌性脑膜脑炎的病理学：对27例患者的分析及发病机制探讨
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The primary pulmonary lymph node complex of crytptococcosis.隐球菌病的原发性肺淋巴结复合体。
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一名新冠肺炎患者的隐球菌血症：病例报告

Cryptococcemia in a patient with COVID-19: A case report.

作者信息

Khatib Mohamad Y, Ahmed Amna A, Shaat Said B, Mohamed Ahmed S, Nashwan Abdulqadir J

机构信息

Critical Care Medicine Department Hazm Mebaireek General Hospital (HMGH) Hamad Medical Corporation (HMC) Doha Qatar.

Critical Care Medicine Department Hamad General Hospital (HGH) Hamad Medical Corporation (HMC) Doha Qatar.

出版信息

Clin Case Rep. 2020 Dec 19;9(2):853-855. doi: 10.1002/ccr3.3668. eCollection 2021 Feb.

DOI:10.1002/ccr3.3668
PMID:33598258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7869327/
Abstract

The authors urge clinicians to balance the use of Immunosuppressant drugs and tocilizumab for COVID-19 patients to avoid the development of infections like Cryptococcemia, leading to death within 30 days.

摘要

作者敦促临床医生在为新冠肺炎患者使用免疫抑制药物和托珠单抗时要权衡利弊，以避免出现如隐球菌血症等感染，导致患者在30天内死亡。