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劳伦隐球菌所致真菌血症及非新生隐球菌血症综述

Fungaemia due to Cryptococcus laurentii and a review of non-neoformans cryptococcaemia.

作者信息

Johnson L B, Bradley S F, Kauffman C A

机构信息

Department of Internal Medicine, Veterans Affairs Medical Center, Ann Arbor, MI 48105, USA.

出版信息

Mycoses. 1998 Sep-Oct;41(7-8):277-80. doi: 10.1111/j.1439-0507.1998.tb00338.x.

DOI:10.1111/j.1439-0507.1998.tb00338.x
PMID:9861831
Abstract

Cryptococcus laurentii is one of several non-neoformans cryptococci that have rarely been associated with human infection. The spectrum of clinical infection due to non-neoformans species ranges from skin lesions to fungaemia. Most cases of non-neoformans fungaemia have been nosocomially acquired and have been associated with indwelling intravascular catheters and neutropenia. Limited data on in vitro susceptibilities of non-neoformans cryptococci show these species to be more resistant to fluconazole and flucytosine than most Cr. neoformans. Two such cases are presented here.

摘要

罗伦隐球菌是几种非新生隐球菌之一,很少与人类感染相关。非新生隐球菌属导致的临床感染范围从皮肤病变到真菌血症。大多数非新生隐球菌属真菌血症病例是医院获得性的,并且与留置血管内导管和中性粒细胞减少有关。关于非新生隐球菌体外药敏性的有限数据表明,这些菌种比大多数新生隐球菌对氟康唑和氟胞嘧啶更具耐药性。本文介绍两例此类病例。

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