Hughes J C, Votaw M L
Cancer. 1979 Sep;44(3):1150-4. doi: 10.1002/1097-0142(197909)44:3<1150::aid-cncr2820440353>3.0.co;2-u.
Two patients with multiple myeloma are described in whom an unusual complication developed: pleural effusion containing myeloma cells. There are 7 previously reported cases of myeloma in the English literature with this type of effusion. Pleural effusion in myeloma may be due to plasma cell infiltration of the pleura, congestive heart failure, pulmonary embolism, nephrotic syndrome, and second neoplasms. In view of these multiple etiologies, diagnostic thoracentesis should be performed in order to treat the effusion appropriately.
本文描述了两名多发性骨髓瘤患者，他们出现了一种不寻常的并发症：含有骨髓瘤细胞的胸腔积液。英文文献中此前有7例骨髓瘤患者出现过这种类型的积液。骨髓瘤患者出现胸腔积液可能是由于浆细胞浸润胸膜、充血性心力衰竭、肺栓塞、肾病综合征以及继发性肿瘤。鉴于病因多样，应进行诊断性胸腔穿刺术以便对积液进行恰当治疗。
