患有13三体综合征的不一致性单卵双胞胎。
Discordant monozygotic twins with trisomy 13.
作者信息
Loevy H T, Miller M, Rosenthal I M
出版信息
Acta Genet Med Gemellol (Roma). 1985;34(3-4):185-8. doi: 10.1017/s0001566000004712.
PMID:3832730
Abstract
Monozygotic twins with typical trisomy 13 are reported. Despite an identical karyotype, the twins were dimorphic for the presence of an omphalocele. Reasons for the rarity of MZ twins with trisomy 13 are presented. It is suggested that the presence of a chromosomal abnormality in MZ twins may predispose to dimorphism.
摘要
据报道，有一对单卵双胞胎患有典型的13三体综合征。尽管核型相同，但这对双胞胎在脐膨出的表现上却存在差异。文中阐述了单卵双胞胎患13三体综合征较为罕见的原因。有人提出，单卵双胞胎中存在染色体异常可能易导致表现型差异。
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引用本文的文献
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Monozygotic twins with trisomy 18: a report of discordant phenotype.18三体综合征的单卵双胞胎：不一致表型的报告
J Med Genet. 1990 Oct;27(10):640-2. doi: 10.1136/jmg.27.10.640.
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