Heinonen P K, Koivula T, Pystynen P
Acta Obstet Gynecol Scand. 1985;64(8):649-52. doi: 10.3109/00016348509158207.
Peripheral serum concentrations of progesterone were measured in 27 postmenopausal women with malignant, borderline, or benign ovarian tumor and in 10 women without ovarian neoplasm. The progesterone levels were significantly higher in all ovarian tumor groups as compared with the controls. There was no difference between malignant and benign tumors. Patients with a tumor volume over 1 000 ml had higher progesterone levels than patients with smaller tumors, in both peripheral and ovarian venous blood. Mucinous ovarian tumors were associated with the highest progesterone levels, compared with other histologic types of ovarian tumor. The results indicate that mucinous ovarian tumors are able to secrete progesterone and that the stage of malignancy has no effect on this hormonal activity.
对27名患有恶性、交界性或良性卵巢肿瘤的绝经后女性以及10名无卵巢肿瘤的女性测定了外周血清孕酮浓度。与对照组相比，所有卵巢肿瘤组的孕酮水平均显著更高。恶性肿瘤和良性肿瘤之间无差异。肿瘤体积超过1000毫升的患者，其外周血和卵巢静脉血中的孕酮水平均高于肿瘤较小的患者。与其他组织学类型的卵巢肿瘤相比，黏液性卵巢肿瘤的孕酮水平最高。结果表明，黏液性卵巢肿瘤能够分泌孕酮，且恶性程度对这种激素活性没有影响。
